Southwest Research Institute (SwRI) is a premier independent, nonprofit research and development organization using multidisciplinary services to provide solutions to some of the world’s most challenging scientific and engineering problems. Headquartered in San Antonio, Texas, our client-focused, client-funded organization occupies more than 2.4 million square feet of laboratories, test facilities, workshops, and offices for more than 3,000 employees who perform contract work for government and industry clients.
SwRI provides pharmaceutical services, under ISO 9001:2015, ranging from early drug discovery through formulation and CGMP manufacturing. SwRI is a recognized leader in microencapsulation and controlled release and has conducted numerous drug delivery projects utilizing all routes of administration. Our formulation expertise includes micro- and nanoparticles, emulsions, suspensions, fibers, and films to reduce toxicity as well as optimize stability, bioavailability, and dissolution rate. Our unique Rhodium™ small molecule/protein docking platform allows rapid binding site identification and in silico screening. We provide analog synthesis, lead selection, optimization, characterization, and scale-up services to include CGMP manufacturing of APIs (active pharmaceutical ingredients) and final dosage forms for clinical trials.
SwRI also offers services in the fields of biomanufacturing, regenerative medicine, cellular expansion and therapeutics, biosensors, additive manufacturing, hot melt extrusion, 3D printing, and medical devices. Medical device research and development can be performed under an ISO 13485 and CGMP-compliant Quality Management System to produce devices and products suitable for pre-clinical and clinical trials which are compliant with published FDA guidance.