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Formulation and Delivery
Hot Topic

Hot Topic: Intelligent Nano-/Micro-Robots as a Drug-Carrier for Therapeutic Advancement

Monday, October 21, 2024
9:00 AM – 10:00 AM MT
Location:155 A

Formulation and Delivery Hot Topic

    Hot Topic Speaker(s)

  • Joseph Wang, PhD (he/him/his)

    SAIC Endowed Chair, Distinguished Professor
    Department of Nanoengineering University California San Diego (UCSD)
    La Jolla, California

  • Minjun Kim, PhD

    Robert C. Womack Endowed Chair Professor in Engineering
    Southern Methodist University

    • Hot Topic Moderator(s)

  • Vibhuti Agrahari, PhD

    Asst. Prof.
    University of Oklahoma Health Sciences Center, Oklahoma

Nanoscale robots that can effectively convert diverse energy sources into movement and forces represent a rapidly emerging and fascinating robotic research area. Such nanoscale robots offer impressive capabilities, including greatly enhanced power and cargo-towing forces, multi-functionality, easy surface functionalization, and versatility. The new capabilities of modern nanorobots indicate immense potential for a variety of biomedical applications, and should have major impact on disease diagnosis, treatment, and prevention. Recent in vivo applications using different types of biocompatible and biodegradable microrobots will be illustrated, including enhanced drug delivery towards enhanced treatment of stomach or lung infections, active vaccine delivery, autonomous gastric fluid neutralization, microrobot pills for oral delivery, or efficient intracellular delivery of functional proteins and nucleic acids.

Learning Objectives:

  • Demonstrate therapeutic applications of micro/nanorobots in oncology, neurological disorders, ophthalmic diseases, cardiovascular diseases, vaccine delivery, antibiotic delivery, regenerative medicine and cell-based therapy.
  • Interpret the knowledge gaps in nanorobots R&D and scale-up developments, bio-responsive strategies, biocompatibility issues, and targeted drug delivery.
  • Describe the translational challenges and critical design factors of micro/nanorobots and explore the collaboration opportunities for drug delivery applications.
  • Discuss the advanced capabilities of microrobots.
  • Demonstrate the advantages of active drug carriers (compared to common passive ones)