Postdoctoral Fellow
Amgen Inc.
Since joining Amgen as a Postdoctoral Fellow, I have contributed to the establishment of in vitro ADME assay toolkit for the study of biologics, including robust cell-based methods to establish in vitro to in vivo correlations (IVIVC) for therapeutic proteins. I have developed and implemented a range of bioanalytical, biophysical, and immunoassays to study pharmacokinetics of biologics comprising different molecular formats. I characterize cell lines, and conduct cellular trafficking studies to evaluate the pharmacokinetics of large molecules. I'm contributing to enhance Amgen's early-stage pharmacokinetic assessment capabilities, as well as align with the ethical principles by potentially reducing animal usage during candidate selection and minimizing late-stage molecule attrition due to unforeseen pharmacokinetic challenges.
My research interests and expertise lie in the areas of different bioanalytical and biophysical assay development, cellular functional assay development, and large molecule DMPK. Before joining Amgen, I completed my PhD in Pharmaceutical and Chemical Sciences with a major in Drug Targeting and Delivery from University of the Pacific. I am passionate about advancing the science and technology of drug discovery and development, and contributing to the improvement of human health.