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Sibylle Neuhoff, PhD (she/her/hers)

Senior Scientific Advisor & Deputy Head of Translational Sciences (DMPK)
Certara Predictive Technologies
Sheffield, England, United Kingdom

Dr. Sibylle Neuhoff is a Senior Scientific Advisor and Deputy Head of the Translational Science Group at Certara Predictive Technologies, where she leads the Transporter Group within Simcyp. With over 25 years of experience in the fields of transport, transporters, and their mechanisms, Sibylle is a recognized expert in PBPK/PD modeling, oral drug absorption, transport, metabolism, and toxicity. Her extensive research is documented in numerous peer-reviewed journal articles (Sibylle Neuhoff (0000-0001-8809-1960) – ORCID).

Sibylle holds a degree in Chemistry from the Goethe University in Frankfurt am Main, Germany, and earned her PhD from the Department of Pharmacy at Uppsala University, Sweden, in 2006. Her current research focuses on the pharmacogenomics of drug-metabolizing enzymes and transporters, drug disposition and pharmacodynamics, ligand interactions with human metabolizing enzymes and transporters, endogenous biomarkers, and innovative approaches to simulate and predict metabolic clearance, drug-drug interactions, and transporter-related interactions in both healthy subjects and patient populations.

Sibylle has taught over 50 PBPK workshops on the Simcyp™ PBPK Simulator, Simcyp Animal, and the Simcyp In Vitro Data Analysis (SIVA) toolkit, covering topics such as MIDD, Transporter, FIH, DDI, and Best Practices. She is regularly invited as speaker to present at national and international conferences and meetings.

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