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Punit Marathe, PhD

Vice President DMPK-TOX
Agios Pharmaceuticals
Princeton Jct, New Jersey

Punit Marathe is currently a VP of DMPK, Clinical Pharmacology and Toxicology at Agios Pharmaceuticals, USA where she is responsible for discovery and development of new drugs for rare diseases. Prior to joining Agios, she served as executive director of integrated drug discovery and capabilities at Syngene International. Punit spent most of her career at Bristol-Myers Squibb and retired as the global head of Metabolism and Pharmacokinetics. Dr. Marathe has extensive experience in multiple areas of Drug Metabolism and Pharmacokinetics including drug discovery, lead optimization, preclinical and clinical pharmacokinetic studies leading to product registration and life-cycle management. In her 30-year career, she was involved in the characterization of small molecule and biologic drug disposition from early discovery to commercialization, collaborating with drug discovery and Clinical Pharmacology for selection, optimization and characterization of lead candidates from multiple projects. Punit’s span of responsibilities included characterizing ADME profile of lead candidates, establishing PK-PD relationships in animal disease models, projecting human pharmacokinetic profile and efficacious doses, guiding selection of doses for FIH studies, characterizing human ADME profile and understanding drug-drug interactions liabilities. Dr. Marathe has published over 100 publications and has presented at multiple national and international conferences.

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