Professor
University of Missouri-Columbia
Columbia, Missouri
Wendy Picking, PhD, Professor of Veterinary Pathobiology at the University of Missouri, received a BA in Biochemistry and a PhD in Molecular Genetics at the University of Kansas. She did post-doctoral fellowships at the University of Texas, Saint Louis University and Washington University in St. Louis. She was a research assistant professor at KU where she began working on the type III secretion apparatus (T3SA) of Shigella flexneri, causative agent of bacillary dysentery. She identified IpaD as the T3SA needle tip protein. During her tour of the central plains at Oklahoma State University Microbiology and Molecular Genetics, KU Department of Pharmaceutical Chemistry, and University of Missouri-Columbia, her team developed a self-adjuvanting fusion protein subunit vaccine, which protected against Shigella spp. She then developed a similar vaccine to Pseudomonas aeruginosa that protects against an acute pneumonia in mice and rabbits, against a chronic infection in cystic fibrosis rats and against wound infections in rats. Finally, a MRSA protein was added to the P. aeruginosa which protected rabbits against Pa and MRSA.
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A Dual Prophylactic/therapeutic Vaccine Against Pseudomonas Aeruginosa
Wednesday, October 23, 2024
9:00 AM – 9:30 AM MT