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Discovery and Basic Research
Prologue

Prologue: Methods to Assess the Targeted Brain Drug Delivery in Preclinical Settings

On Demand
Location:Online Only

Discovery and Basic Research

The presentation focuses on methods to assess the targeted brain drug delivery including microdialysis, CMA, CMA-ROI, and qMSI-uD methods.

To view all Prologues, visit our library here and click "Enroll".

Learning Objectives:

  • Explain Kp,uu,brain neuroPK parameter, provide its definition and interpretation of numerical values
  • Understand the advantages and disadvantages of microdialysis as a technique for the assessment of unbound concentrations
  • Familiarize with the Combinatory Mapping Approach (CMA), CMA for Regions of Interest (CMA-ROI) and CMA-ROI for quantitative Mass Spectrometry Imaging (qMSI-uD) methods.