Formulation and Delivery
Mitali Bhagwat, MPharm, MBA
Strategic Product Manager – Excipients Solid Application
MilliporeSigma a Business of Merck KGaA
Darmstadt, Hessen, Germany
Description: In recent years several approaches have been developed to screen for co-crystals computationally to tackle increasing solubility challenges. MilliporeSigma has developed mPredict™, a co-crystal prediction tool using the combination of quantum chemistry calculations and statistical thermodynamics while calculating excess enthalpies. Backed with artificial intelligence algorithms, our tool can be utilized to predict co-crystal formation and hence optimum co-formers for your API. It shows strong improvement over physical modelling and is three times more effective than random digital testing.