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Formulation and Delivery
Chalk Talk

Enhancing API Solubility and Bioavailability Using Novel Formulation Techniques

Monday, October 21, 2024
12:30 PM – 1:15 PM MT
Location:Spotlight Stage C, Aisle 2800, Exhibit Hall

Sponsored By 
Formulation and Delivery Partner Presentation-Formulation

    Chalk Talk Presenter(s)

  • Andrew Buis, MS

    Senior Formulation Scientist
    Altasciences
    Harleysville, Pennsylvania

  • Anthony James

    Director of Business Development
    Altasciences
    Laval, Quebec, Canada

Description: The pharmaceutical industry continually faces the challenge of poor solubility in active pharmaceutical ingredients (APIs), which significantly impacts drug bioavailability and therapeutic efficacy.
This presentation delves into two techniques—nanomilling and liquid-filled hard-shell capsule (LFHC) technologies— which aid in overcoming API solubility challenges. Nanomilling significantly reduces API particle size, increasing the surface area and enhancing dissolution rates, while LFHC technology encapsulates APIs in a liquid medium, providing a versatile platform for delivering poorly soluble drugs.

Learning Objectives:

  • Discover common solubility and bioavailability challenges in drug development
  • Understand the mechanisms of Nanomilling and LFHC techniques
  • Evaluate the practical applications and advantages of each technique