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Preclinical, Clinical and Translational Sciences
Partner Presentation

You're hired! Selecting the Right Pre-IND Compound

Monday, October 21, 2024
9:00 AM – 10:00 AM MT
Location:360 Stage #3, Exhibit Hall

Sponsored By 
Preclinical & Translation Sciences Partner Presentation-Preclinical

    Partner Presentation Speaker(s)

  • Darren Matthews, PhD

    Associate Science Director
    Charles River
    Wilmington, Massachusetts

  • ER

    Eleanor Row

    Executive Director
    Quotient Sciences
    Nottingham, England, United Kingdom

Description: With up to 95 % of small molecules failing to transition from Discovery through to Clinic, the selection of the right candidate is an essential step to increase the chances of success. Understanding potential pitfalls in the following areas are absolute key to selecting the right candidate:
1. The chemical synthetic route
2. The solid form properties
3. Physicochemical properties
The presenters will provide insights from their shared experiences of what to look for when selecting candidates.

Learning Objectives:

  • Understand the point in the development pathway that preclinical candidate properties should be considered.
  • Understand how working with a dedicated partner can help accelerate the process.
  • Understand the consequences of poor compound selection and some of the ways this can be mitigated.