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Formulation and Delivery
Partner Presentation

Evaluation of Solid Self-Emulsifying Drug Delivery System by Fluid-Bed Technology

Wednesday, October 23, 2024
10:30 AM – 11:30 AM MT
Location:360 Stage #1, Exhibit Hall

Sponsored By 
Formulation and Delivery Partner Presentation-Formulation

    Partner Presentation Speaker(s)

  • TG

    Tasneem Gandhi, n/a

    Project Manager
    Glatt Group - Pharmaceutical Services CDMO Unlimited
    Ramsey, New Jersey

Description: The focus of this study is to demonstrate the feasibility of scale-up manufacture of solid SEDDs using Ritonavir as a model compound. Solid SEDDs prepared by the Fluid-Bed process potentially allow re-dispersibility, solid state properties of drug substances, increased solubility, and bioavailability. The potential advantages of preparing solid SEDDS by fluid-bed technology are that it will be a one-step process, fast drug release, and various drug-release profiles when modified using various release-controlling polymers.

Learning Objectives:

  • Can compressible SEDDs be manufactured from a fluid-bed granulation?
  • Fluid-bed granulation may allow a shorter processing time to convert liquid-state SEDDs into free-flowing granules with micellar structure when reconstituted in a suitable medium.
  • Potentially the solid SEDDs prepared by fluid-bed can allow different release profiles with additional coating and excipients.