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Manufacturing & Analytical Characterization
Partner Presentation

Hydroxypropyl Beta-Cyclodextrin as a Safer Alternative for Viral Inactivation in Bioprocessing

Monday, October 21, 2024
2:00 PM – 3:00 PM MT
Location:360 Stage #2, Exhibit Hall

Sponsored By 

Looking for Triton-X alternative in your bioprocessing?
This work introduces hydroxypropyl Beta-Cyclodextrin (HPBCD) as a promising solution for viral inactivation in bioprocessing. HPBCD effectively inactivates enveloped viruses and integrates seamlessly into downstream processes without affecting product stability and purification efficiency. Due to its established use as an excipient in many approved injectables, it significantly reduces regulatory hurdles compared to other viral inactivating alternatives involving newly synthesized chemicals. HPBCD offers a safe, efficient, and process-compatible option for viral clearance in bioprocessing.

Learning Objectives:

  • Learn about Hydroxypropyl Beta-Cyclodextrin as a Safer Alternative for Viral Inactivation in Bioprocessing.
  • Learn how to incorporate Hydroxypropyl Beta-Cyclodextrin in your bioprocessing step for viral inactivation.
  • Demonstrate the process compatibility of Hydroxypropyl Beta-Cyclodextrin in downstream processes.