Industry 4.0, also known as the Fourth Industrial Revolution (4IR), will result in the digital transformation of the manufacturing sector. It is propelled by transformative trends such as the proliferation of data and connectivity, advancements in analytics, human–machine collaboration, and enhancements in robotics. Biopharmaceutical manufacturers are also giving significant attention to automation and data analytics so as to embrace Industry 4.0. This talk will focus on technologies and approaches that will enable Next-Generation manufacturing of biopharmaceuticals. Case studies will be presented to showcase the various elements that are foundational for this transition. These include digital twins of biopharmaceutical unit operations and processes, mechanistic modeling, real-time process monitoring, statistical process control, model-based control, and risk assessment. Case studies will illustrate how application of these concepts can facilitate consistency in process and product quality attributes, enhance productivity, and reduce cost of manufacturing. Constraints or challenges that hinder adoption of Industry 4.0 and soon Industry 5.0 in biopharmaceutical manufacturing will be mentioned.
Learning Objectives:
Upon completion, participant will be able to understand key challenges that are faced when implementing next generation manufacturing
Upon completion, participant will become aware of some of the successful strategies that a manufacturer can adopt to alleviate above mentioned challenges
Upon completion, participant will become aware of the latest process and analytical technologies in biopharmaceutical manufacturing
