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Poster Schedule
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Poster Schedule
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Mon, Oct 21
Tue, Oct 22
Wed, Oct 23
Poster Schedule
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Monday, October 21, 2024
9:30 AM – 10:30 AM
MT
(M0930-01-01) Graphical Design Space for the Primary Drying Phase of Freeze Drying: Factors Affecting the Dried Product Layer Resistance
Favorite
9:30 AM – 10:30 AM
MT
(M0930-01-03) Overcoming Direct Compression Issues in Omeprazole Formulations Using Co-Processed Excipient vs. Wet Granulation
Favorite
9:30 AM – 10:30 AM
MT
(M0930-01-04) Integrated Approach to Enhance Formulation Robustness in Multiparticulate Formulations
Favorite
9:30 AM – 10:30 AM
MT
(M0930-01-05) Lipid-Stabilized Nanocrystal Vesicles for Cheat-Free Testing of Novel Drugs: The Case of Zuranolone
Favorite
9:30 AM – 10:30 AM
MT
(M0930-01-06) Implementing Co-processed API to Enable High-Drug-Load Formulation for Direct Compression
Favorite
9:30 AM – 10:30 AM
MT
(M0930-02-07) Comparative Analysis of Pharmacokinetics and Drug-Drug Interactions in Microdosing Cocktail Studies Using Physiologically-Based Pharmacokinetic Modeling
Favorite
9:30 AM – 10:30 AM
MT
(M0930-02-08) Evaluation of Amorphous and Lipid-Based Formulation Strategies to Increase Oral Cannabidiol Bioavailability
Favorite
9:30 AM – 10:30 AM
MT
(M0930-02-09) Predicting Bioequivalence with the COMPASS Tool - Analysis of the Experimental and Literature Data
Favorite
9:30 AM – 10:30 AM
MT
(M0930-02-10) Multiplexed Cytokine Measurements in Culture Supernatants upon Ex Vivo Stimulation of Human PBMCs to Assess Cellular Immune Response in Vaccine Studies
Favorite
9:30 AM – 10:30 AM
MT
(M0930-02-11) Toxicokinetics of 23ME-01473, a Novel Anti-ULBP6/2/5 Monoclonal Antibody, in Cynomolgus Monkeys Following Intravenous Bolus Injections in a 4-Week Toxicity Study
Favorite
9:30 AM – 10:30 AM
MT
(M0930-02-12) Sex, Racial, and Ethnic Representation in COVID-19 Vaccine Clinical Trials Conducted in US - A Systematic Review Compared to 2020 US Census Data
Favorite
9:30 AM – 10:30 AM
MT
(M0930-03-13) Tuning the Organ Selectivity of mRNA Expression through Dendrimer-Based Lipid Nanoparticles
Favorite
9:30 AM – 10:30 AM
MT
(M0930-03-14) Styl’One Nano Compaction Simulation Studies and Utilization of a Digital Tableting Platform in Formulation Development
Favorite
9:30 AM – 10:30 AM
MT
(M0930-03-16) Optimizing Storage Conditions to Maintain Chemical Stability and Aerodynamic Performance of Tigecycline Inhalation Powder
Favorite
9:30 AM – 10:30 AM
MT
(M0930-03-17) Heterologous Microneedle Vaccine Strategy for COVID-19
Favorite
9:30 AM – 10:30 AM
MT
(M0930-03-18) Evaluating the Versatility of Klucel™ Xtend HPC in Dual Active Allergy Relief Extended-Release Dosages
Favorite
9:30 AM – 10:30 AM
MT
(M0930-04-19) Genetically Engineered PD-L1 Targeted Exosomes for Immunotherapy of Doxorubicin Resistant Triple Negative Breast Cancers
Favorite
9:30 AM – 10:30 AM
MT
(M0930-04-20) An Innovative Dual Action Antibiotic Adjuvant Strategy Using Ionic Liquid toward Synergistic Restoration of Activity in MDRO and Enhancing Antimicrobial Activity Against MRSA
Favorite
9:30 AM – 10:30 AM
MT
(M0930-04-21) Evaluation of the Blood-Brain Barrier Protective Effects of Metformin after Mixed Exposures to Cigarette Smoke, e-Cigarette Vapor, and Stroke Conditions
Favorite
9:30 AM – 10:30 AM
MT
(M0930-04-22) A Catalytic Aldicarb Bioscavenger as a Treatment for Aldicarb Poisoning
Favorite
9:30 AM – 10:30 AM
MT
(M0930-04-24) Role of FLVCR2 in the Intestinal Choline Uptake in the Rat Model
Favorite
9:30 AM – 10:30 AM
MT
(M0930-05-25) Cocrystallization Improves the Tabletability of Ligustrazine Despite a Reduction in Plasticity
Favorite
9:30 AM – 10:30 AM
MT
(M0930-05-26) Advancing the Use of Chimeric Antigen Receptor T-cell Therapy (CAR T) in Glioblastoma Treatment
Favorite
9:30 AM – 10:30 AM
MT
(M0930-05-27) Non-woven Polymeric Fiber Mats for Female-Initiated On-Demand Contraception Without Hormones
Favorite
9:30 AM – 10:30 AM
MT
(M0930-05-28) Disulfiram-Loaded Metal-Organic Nanoparticles Trigger Immunogenic Cell Death of the Triple-Negative Breast Cancer
Favorite
9:30 AM – 10:30 AM
MT
(M0930-05-29) Exploring the Effect of Manufacturing Methods in Long-Acting Injectable Formulation Characteristics
Favorite
9:30 AM – 10:30 AM
MT
(M0930-05-30) Sotorasib Nanosuspension: A Patient-Centric Approach to Improve Oral Absorption and Overcome Limitations Associated with Current Treatment
Favorite
9:30 AM – 10:30 AM
MT
(M0930-06-31) Parallel Accelerator and Molecular Mass Spectrometry for Tracing
14
C-Labeled Metabolites
Favorite
9:30 AM – 10:30 AM
MT
(M0930-06-32) Development of Quantitative MALDI Mass Spectrometry Imaging Methods for Studying Distribution of Antituberculosis Drugs at Their Site of Action
Favorite
9:30 AM – 10:30 AM
MT
(M0930-06-34) Development and Qualification of an ECLIA Method for the Detection of Fremanezumab in Human CSF
Favorite
9:30 AM – 10:30 AM
MT
(M0930-06-35) Harnessing Camel Milk-Derived Exosomes to Enhance Oral Bioavailability of Anticancer Agents with Poor Solubility and Permeability (ARV-825 and CBD) and Revealing the Mechanism of Improved Absorption
Favorite
9:30 AM – 10:30 AM
MT
(M0930-06-36) 1-Tiered Approach for Anti-drug Antibody Testing in Clinical Study
Favorite
9:30 AM – 10:30 AM
MT
(M0930-07-37) Enabling Oral Delivery of Therapeutic Peptide Salmon Calcitonin: Impact of Hydrophobic Ion Pairs and Self-Nanoemulsifying Drug Delivery Systems on Proteolytic Protection and Pharmacological Activity
Favorite
9:30 AM – 10:30 AM
MT
(M0930-07-38) Evaluating Mucoadhesion of Polymer Films Using Wax Substrates with Mucin Coating
Favorite
9:30 AM – 10:30 AM
MT
(M0930-07-40) Application of Binder Jetting to Develop 3D Printed Modified Release Tablets
Favorite
9:30 AM – 10:30 AM
MT
(M0930-07-41) Development and Evaluation of Buprenorphine Sublingual Formulation for the Treatment of Neonatal Opioid Withdrawal Syndrome
Favorite
9:30 AM – 10:30 AM
MT
(M0930-09-48) Data-Driven Prediction of Translational Formulation Strategies for Poorly Water-Soluble Drug Molecules: Machine Learning to Minimize Trial and Error in Early Formulation Development
Favorite
9:30 AM – 10:30 AM
MT
(M0930-09-49) Formulation Development of Simvastatin Self-Emulsifying Drug Delivery System Using Hot Melt Extrusion
Favorite
9:30 AM – 10:30 AM
MT
(M0930-09-50) Predicting Filaments Behavior in Milling and Printing via 3 Point Bend Test
Favorite
9:30 AM – 10:30 AM
MT
(M0930-09-51) Improvements in Liposomal Manufacturing Technology
Favorite
9:30 AM – 10:30 AM
MT
(M0930-10-54) Utilization of Proteomic Surrogates for Early Detection of Unexpected Drug Benefits
Favorite
9:30 AM – 10:30 AM
MT
(M0930-10-55) Protective Effects of Angiotensin Receptor Blockers on Knee Joint Cartilage Volume: A Retrospective Analysis of Osteoarthritis Initiative Study
Favorite
9:30 AM – 10:30 AM
MT
(M0930-10-56) Evaluating Food Effects in Oral Drug Delivery Using a Combination of PBPK Modeling and Molecular Dynamics Simulations
Favorite
9:30 AM – 10:30 AM
MT
(M0930-10-57) Open Label, Single Center, 2 Part Parallel Study to Determine the Absolute Bioavailability and the Absorption, Metabolism, and Elimination Properties of [
14
C]E7386 in Healthy Male Subjects
Favorite
9:30 AM – 10:30 AM
MT
(M0930-10-58) Protein Engineering Strategies to Overcome High Target-Independent Clearance of Monoclonal Antibodies Due to Charge-Driven Liabilities
Favorite
9:30 AM – 10:30 AM
MT
(M0930-10-59) Validation of a Quantitative PCR (qPCR) Assay for the Detection and Quantification of Replication Competent Lentivirus for Patient Monitoring in Lentiviral Vector-Based Cell Therapy Studies
Favorite
9:30 AM – 10:30 AM
MT
(M0930-11-60) Improving the Stability of RNA Lipid Nanoparticles Using the Innovative Spray-Freeze Drying Technique
Favorite
9:30 AM – 10:30 AM
MT
(M0930-11-61) Investigating Impact of Food Induced Fluid Viscosity on Immediate Release Tablet Disintegration and Drug Dissolution
Favorite
9:30 AM – 10:30 AM
MT
(M0930-11-62) Topical Creams Sensorial Perception: Correlation with Product Critical Quality Attributes
Favorite
9:30 AM – 10:30 AM
MT
(M0930-11-63) The Effect of Annealing Temperature and Composition on Lyophilized Sucrose / Glycine Formulations
Favorite
9:30 AM – 10:30 AM
MT
(M0930-11-64) Low Surface Area Measurements of Excipients, Replacing Krypton with Nitrogen
Favorite
9:30 AM – 10:30 AM
MT
(M0930-11-65) Optimization of a Mini-Tablet Compression Process
Favorite
10:30 AM – 11:30 AM
MT
(M1030-01-01) Engineering of Layer-By-Layer “Smart” Acetate Coated Paclitaxel Loaded Polylactic-Co-Glycolic Acid Nanoparticles to Treat Prostate Cancer In Vitro
Favorite
10:30 AM – 11:30 AM
MT
(M1030-01-02) Development of Tretinoin-loaded Lipid Nanoparticles for Topical Drug Delivery
Favorite
10:30 AM – 11:30 AM
MT
(M1030-01-03) Reverse Engineering of Nexplanon
®
Contraceptive Implant: Physicochemical Properties and In Vitro Drug Release
Favorite
10:30 AM – 11:30 AM
MT
(M1030-01-04) Development of Extrusion-Based 3D Printed Hydrophilic Polymeric Transdermal Films of Pramipexole Dihydrochloride for Parkinson’s disease
Favorite
10:30 AM – 11:30 AM
MT
(M1030-01-05) Novel Combination Approach to Enhance Solubility and Permeability of Pazopanib Using Phospholipid Complex and a Bioenhancer
Favorite
10:30 AM – 11:30 AM
MT
(M1030-01-06) Supersolubilization and Amorphization of a Weakly Acidic Drug, Flurbiprofen, by Applying Acid-Base Supersolubilization (ABS) Principle
Favorite
10:30 AM – 11:30 AM
MT
(M1030-02-07) Review of First-in-Human Trials for Gene Therapy in Ocular Diseases
Favorite
10:30 AM – 11:30 AM
MT
(M1030-02-08) Mechanistic Mathematical Modeling of In Vitro Drug Release from PLGA-Based Dexamethasone Solid Implants
Favorite
10:30 AM – 11:30 AM
MT
(M1030-02-09) Integration of Gut Microbiome Metabolism in a PBBM-PBPK Model: Its Impact on the Sulfasalazine Absorption
Favorite
10:30 AM – 11:30 AM
MT
(M1030-02-10) Exploring the Influence of Dietary Components and Excipients on Intestinal Lymphatic Drug Absorption: Findings from an Advanced In Vitro Approach
Favorite
10:30 AM – 11:30 AM
MT
(M1030-02-11) Demonstration of Virtual Bioequivalence (VBE) Between Progesterone Vaginal Rings Using Mechanistic Vaginal Absorption and Metabolism Model (MechVAM) Within Simcyp Simulator
Favorite
10:30 AM – 11:30 AM
MT
(M1030-02-12) Investigating Differences in the Pharmacokinetics of Monoclonal Antibodies in Japanese and Non-Japanese Subjects
Favorite
10:30 AM – 11:30 AM
MT
(M1030-03-13) Cationic Peptide Anchor-Mediated Binding to Tumor Extracellular Matrix Improves Intratumoral Retention of Agonist CD40 Antibody
Favorite
10:30 AM – 11:30 AM
MT
(M1030-03-14) Enhancing Glycyrrhizin Delivery to White Adipose Tissue: A Promising Approach for Safe and Effective Obesity Treatment
Favorite
10:30 AM – 11:30 AM
MT
(M1030-03-15) Formulation-Related Influences on the Ex Vivo Permeation of Lidocaine Hydrochloride Films
Favorite
10:30 AM – 11:30 AM
MT
(M1030-03-16) Development and Characterization of PLGA Tip-Loaded Polymeric Microneedles for the Sustained, Week-Long Release of a Lipophilic Molecule-Carfilzomib
Favorite
10:30 AM – 11:30 AM
MT
(M1030-03-17) Bioresponsive Hydrogel Compositions Designed to Fortify Natural Contraceptive Barrier Properties of the Cervicovaginal Environment in Humans
Favorite
10:30 AM – 11:30 AM
MT
(M1030-04-19) Integrated Screening Platform of PDE for Lung Fibrosis Drug Discovery
Favorite
10:30 AM – 11:30 AM
MT
(M1030-04-20) A Physiologically Based Pharmacokinetic Model of
18
F-FMAU to Accompany Positron Emission Tomography in Humans
Favorite
10:30 AM – 11:30 AM
MT
(M1030-04-21) Overexpression of Human ApoC3 in Mice Leads to Hypertriglyceridemia and Induces Key CVD-related Lipid Biomarkers
Favorite
10:30 AM – 11:30 AM
MT
(M1030-04-22) Amyloid Beta Peptides Inhibit Insulin Trafficking at the Blood-Brain-Barrier in Alzheimer's disease Brain
Favorite
10:30 AM – 11:30 AM
MT
(M1030-04-23) Formulation of a Triple-Action Nanoemulgel for Mild to Moderate Atopic Dermatitis: Impact on Skin's Mechanical and Antibacterial Properties
Favorite
10:30 AM – 11:30 AM
MT
(M1030-04-24) Old Dog Learning a New Trick: Statins as Novel Inhibitors of Vascular PDE1A for Regulating Vasodilation and Blood Pressure
Favorite
10:30 AM – 11:30 AM
MT
(M1030-05-25) Impact of Using 2-Hydroxypropyl-b-cyclodextrin (HPbCD) as an Excipient in Biologic Formulations on Solution Properties and Compatibility
Favorite
10:30 AM – 11:30 AM
MT
(M1030-05-26) Co-Administration of a Novel Hedgehog Inhibitor and Anti-miR-96 in a Lipid-Based Nanosystem for the Treatment of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD)
Favorite
10:30 AM – 11:30 AM
MT
(M1030-05-28) In Vitro and In Vivo Evaluation of Topical 4-phenylbutyric Acid Microsponge Formulation as a Potential Antidote Against Arsenical-Induced Skin Injury
Favorite
10:30 AM – 11:30 AM
MT
(M1030-05-29) Preparation and Characterization of Pregabalin Loaded Liposomes for Topical Drug Delivery: Utilizing the Novel Platform Technology for the Effective Treatment of Neuropathic Pain Management
Favorite
10:30 AM – 11:30 AM
MT
(M1030-05-30) Development of Nanosuspension Loaded Dissolving Microneedles for Delivery of a Novel Combination of Drugs for Treatment of Rheumatoid Arthritis
Favorite
10:30 AM – 11:30 AM
MT
(M1030-06-31) Utilizing LC-MS to Support of PABAD-Based Detection of Neutralizing Antibodies
Favorite
10:30 AM – 11:30 AM
MT
(M1030-06-32) Analytical Considerations of Drug Products Containing Isomeric Active Pharmaceutical Ingredients in Abbreviated New Drug Application (ANDA) Submissions
Favorite
10:30 AM – 11:30 AM
MT
(M1030-06-33) The Application of 19F-NMR in the Analysis of Drug-Related Substances of Leritrelvir (RAY1216) in Human Urine and Fecal Samples to Support a Phase I Clinical Study
Favorite
10:30 AM – 11:30 AM
MT
(M1030-06-34) In Vitro Permeation Test Outlier Data Evaluation during Bioequivalence Assessment of Abbreviated New Drug Applications
Favorite
10:30 AM – 11:30 AM
MT
(M1030-06-35) Development and Optimization of a Highly Sensitive and Selective Anion Exchange Liquid Chromatography with Fluorescence Detection Assay for Quantitation of siRNA Oligonucleotide Therapeutic Compounds
Favorite
10:30 AM – 11:30 AM
MT
(M1030-06-36) Simultaneous Determination of Metabolites from Seven Key Probe Substrates in CYP Inhibition Assay Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Favorite
10:30 AM – 11:30 AM
MT
(M1030-07-37) GRP78 Targeting of Long-Acting Hydra-Elastin-Like Polypeptides (ELPs) Carrying Rapamycin to Breast Cancer
Favorite
10:30 AM – 11:30 AM
MT
(M1030-07-38) Evaluation of In-Use and Accelerated Stability Studies of Platelet Aggregation Inhibitors: Clopidogrel Hydrogen Sulfate
Favorite
10:30 AM – 11:30 AM
MT
(M1030-07-39) Comparative Analysis of Co-Processed AVICEL DG® vs Individual Microcrystalline Cellulose and Anhydrous Dicalcium Phosphate in Tablet Formulation
Favorite
10:30 AM – 11:30 AM
MT
(M1030-07-40) Drug Release Rate Characterization of Double Nanoemulsions (W1/O/W)
Favorite
10:30 AM – 11:30 AM
MT
(M1030-09-48) Polysaccharide Emulsion Gels for Reducing Postoperative Adhesions and Delivering 5-Fluorouracil
Favorite
10:30 AM – 11:30 AM
MT
(M1030-09-49) Selective Laser Sintering 3D Printing for Improved Solubility of Indomethacin: A Study on Amorphous Drug Conversion
Favorite
10:30 AM – 11:30 AM
MT
(M1030-09-50) Rediscovery of Paclitaxel: A Novel Oral Paclitaxel Softgel Capsule Product for Improving Cancer Therapeutics
Favorite
10:30 AM – 11:30 AM
MT
(M1030-09-51) Development of 3D Printed Oral Disintegrating Tablets of Oxcarbazepine Using Co-Processed Excipient
Favorite
10:30 AM – 11:30 AM
MT
(M1030-09-52) Development of a Self-Emulsifying Drug Delivery System (SEDDS) of Fenofibrate Using ZoomLab
TM
Favorite
10:30 AM – 11:30 AM
MT
(M1030-10-54) Use of Povidones and Copovidones as Solubility Enhancers for Itraconazole Using Hot Melt Extrusion
Favorite
10:30 AM – 11:30 AM
MT
(M1030-10-55) Factory-on-a-Pill – a Digital Pill Concept to Deliver Medicines in Space
Favorite
10:30 AM – 11:30 AM
MT
(M1030-10-56) Development and Validation of Biorelevant Multimodal In Vitro Characterization Techniques for Assessing the Adhesiveness Performance of Transdermal Patches
Favorite
10:30 AM – 11:30 AM
MT
(M1030-10-57) A Solution that Improves the Poor Soluble API Dissolution by Using Porous Calcium Silicate FLORITE
®
Favorite
10:30 AM – 11:30 AM
MT
(M1030-10-58) A Comparative Study of Hypromellose Acetate Succinate and HPMCP by Spray Drying Method and Top Spray Method for Solubility Enhancement
Favorite
10:30 AM – 11:30 AM
MT
(M1030-10-59) Polymer Nanovectors for Treating Lung Inflammation
Favorite
10:30 AM – 11:30 AM
MT
(M1030-11-60) Detecting and Identifying Contaminants for Root Cause Analysis: Distinguishing Free Fatty Acid Breakdown Products of Surfactants, Silicone Oil and Protein Aggregates
Favorite
10:30 AM – 11:30 AM
MT
(M1030-11-61) Capsule Customization: Pioneering Automated Production of Patient-Specific Poly-Pills
Favorite
10:30 AM – 11:30 AM
MT
(M1030-11-62) Orthogonal Measurement of Number Concentration Standards for NTA Calibration
Favorite
10:30 AM – 11:30 AM
MT
(M1030-11-63) Investigation of Interplay between API Processing Method and Modified Release Matrix Tablet on Dissolution Performance
Favorite
10:30 AM – 11:30 AM
MT
(M1030-11-64) Thaw Time Prediction for Partially-Filled Bottles of Antibody Solution in Varying Environments – Predictive Statistical Model on CFD-Generated Datasets
Favorite
10:30 AM – 11:30 AM
MT
(M1030-11-65) Characterization of Long-Acting Injectable Formulation for Pre-Clinical Studies Using Accelerated In Vitro Release (IVR) Technique
Favorite
11:30 AM – 12:30 PM
MT
(M1130-01-01) The Importance of Surface Composition and Wettability on the Dissolution Performance of High Drug Loading Amorphous Dispersion Formulations
Favorite
11:30 AM – 12:30 PM
MT
(M1130-01-02) Preparation and Evaluation of Pramipexole Transdermal Patch: In Vitro and In Vivo Study
Favorite
11:30 AM – 12:30 PM
MT
(M1130-01-03) Exploring the Pharmacological Properties of
Spondias mombin
L. Seed Extract
Favorite
11:30 AM – 12:30 PM
MT
(M1130-01-04) Utilizing Hydroxypropyl Methylcellulose (HPMC) and Carrageenan in Nasal Spray Gel with
Andrographis paniculata
Extract for COVID-19 Prevention
Favorite
11:30 AM – 12:30 PM
MT
(M1130-01-05) Novel Cell-Penetrating Peptide-Based Therapy for Treating Atopic Dermatitis
Favorite
11:30 AM – 12:30 PM
MT
(M1130-01-06) Role of Temperature in the Formation of Solid Micellar-Size Nanoparticles of Nonionic Polyoxyethylated Amphiphiles
Favorite
11:30 AM – 12:30 PM
MT
(M1130-02-07) The Significance of Biotransformation in Discovery Research of NCEs (New Chemical Entity): Examples of Unique Case Studies
Favorite
11:30 AM – 12:30 PM
MT
(M1130-02-08) Kinetics of Sutezolid Metabolism to Its Active Metabolite and Identification of the Relevant Drug Metabolizing Enzymes
Favorite
11:30 AM – 12:30 PM
MT
(M1130-02-09) Deciphering Response Patterns to AKT Inhibitor MK2206 in Breast Cancer Patients: Unveiling Signature Profiles
Favorite
11:30 AM – 12:30 PM
MT
(M1130-02-10) Bivariate Statistical Analyses Reveal the Performance of Human FcRn Transgenic Mouse in Predicting Human Pharmacokinetics of Therapeutic Antibodies
Favorite
11:30 AM – 12:30 PM
MT
(M1130-02-11) Toxicokinetics of cNP8, a Fibronectin-Derived Peptides, in Rats and Dogs Following a Single Intravenous Injection in an Expanded Acute Toxicity Study
Favorite
11:30 AM – 12:30 PM
MT
(M1130-02-12) A Mechanistic Rat PBPK Model for Genistein and Its Glucuronide Metabolite: Integrating Liver and Enteric Metabolism with Transporter-Mediated Biliary and Enteroluminal Clearance
Favorite
11:30 AM – 12:30 PM
MT
(M1130-03-14) Development and Characterization of Preservative Free Ocular Formulation
Favorite
11:30 AM – 12:30 PM
MT
(M1130-03-15) Utilization of Gelatin-Oleic Acid Conjugate Solid Dispersion for Enhanced Stability of Water-Labile Drug
Favorite
11:30 AM – 12:30 PM
MT
(M1130-03-17) Enhancing Gonorrhea Vaccine Efficacy: Dosage Response Analysis of a Novel Microparticulate Formulation
Favorite
11:30 AM – 12:30 PM
MT
(M1130-03-18) Model-Informed Approach for Formulation Development of Extended-Release Phenserine Tablets to Mitigate pH-Dependent Degradation
Favorite
11:30 AM – 12:30 PM
MT
(M1130-04-19) Evaluation of Piperine Nanoparticles for FXTAS Treatment via CGG Repeat Drosophila Model
Favorite
11:30 AM – 12:30 PM
MT
(M1130-04-20) Impact of Macrophages on the Dissolution of Long-Acting Injectable Suspensions
Favorite
11:30 AM – 12:30 PM
MT
(M1130-04-21) Rheological Adaptation of Hydrogels as Novel Preclinical In Vitro Model Substitutes for Human Vitreous Body
Favorite
11:30 AM – 12:30 PM
MT
(M1130-04-22) DEC2 Enhancement of Gemcitabine and Oxaliplatin Sensitivity of Pancreatic Cancer Cells through Suppression of IGFBP4
Favorite
11:30 AM – 12:30 PM
MT
(M1130-04-24) Excitatory Amino Acid Transporter 2 (EAAT2): A Novel Therapeutic Target for Treatment of Alzheimer’s Disease (AD)
Favorite
11:30 AM – 12:30 PM
MT
(M1130-05-25) Preclinical Evaluation of Soluplus-Based Amorphous Solid Dispersion of Alectinib: Bioavailability Enhancement and IVIVC Model Establishment
Favorite
11:30 AM – 12:30 PM
MT
(M1130-05-26) Effect of Tumor Grade and Type on ECM-Liposome Interactions Measured by Contact Angle
Favorite
11:30 AM – 12:30 PM
MT
(M1130-05-27) Evaluating the Efficacy of Polyoxyethylene Sorbitan as a Novel Surfactant in Biotherapeutic Antibody Formulations
Favorite
11:30 AM – 12:30 PM
MT
(M1130-05-28) Understanding the Impact of L-leucine on Stability and Inhalation Potential of Dry Powder Protein Formulations
Favorite
11:30 AM – 12:30 PM
MT
(M1130-05-29) Rapid Detection of Formulation Stability for Fast Product Development
Favorite
11:30 AM – 12:30 PM
MT
(M1130-05-30) Colon Targeted Delivery of Nanosuspension Coated Granules of Albendazole tor the Localized Treatment of Colorectal Cancer
Favorite
11:30 AM – 12:30 PM
MT
(M1130-06-31) Phenyl SPE: A Promising Alternative to More Common Oligonucleotide Extraction
Favorite
11:30 AM – 12:30 PM
MT
(M1130-06-32) A Chilled Liquid Handler Deck Enables the Automation of Lipid LC-MS/MS Bioanalytical Assays
Favorite
11:30 AM – 12:30 PM
MT
(M1130-06-33) A Derivatization-Free LCMS Assay for 4β-Hydroxycholesterol
Favorite
11:30 AM – 12:30 PM
MT
(M1130-06-34) Comparison of Platform Sensitivities: Correlation of Endogenous Neurofilament-Light Chain Concentration Determination in Human Serum and K
2
EDTA Plasma across Immunoassay Platforms
Favorite
11:30 AM – 12:30 PM
MT
(M1130-06-35) Maintaining Pristine Structure for High-Purity Isolates: A Combined Method for Nuclei and Mitochondria
Favorite
11:30 AM – 12:30 PM
MT
(M1130-06-36) A Cell-To-Cell Contact Immune System Mimicking In Vitro Overlay Assay: Evaluating Nanoparticle Vaccine Formulations for Adaptive Immunity Responses
Favorite
11:30 AM – 12:30 PM
MT
(M1130-07-37) Inflammatory Response to Lipopolysaccharide-Induced Injury and Treatment with Extracellular Matrix-Derived Nanoparticles
Favorite
11:30 AM – 12:30 PM
MT
(M1130-07-38) An Assessment of Factors Influencing the Integrity of Sprayed-On Silicone Oil Layer in Prefilled Syringes and Functionality of Prefilled Syringes
Favorite
11:30 AM – 12:30 PM
MT
(M1130-07-39) Revolutionizing Drug Formulations: Delayed Release and Sustained Release Using Hypromellose 2208 Types and Hypromellose Acetate Succinate
Favorite
11:30 AM – 12:30 PM
MT
(M1130-07-40) Bilayer Microneedle Array Patch for Transdermal Delivery of Novel Capsid Inhibitor Lenacapavir to Mitigate the Risk of Pediatric HIV Infection
Favorite
11:30 AM – 12:30 PM
MT
(M1130-07-41) Photonic Formulations of Hydroxypropyl Cellulose – Study of Mixtures with a Pharmaceutical Potential
Favorite
11:30 AM – 12:30 PM
MT
(M1130-09-48) CCL2 Microparticles Modulate Host Immune Response in Periodontal Disease
Favorite
11:30 AM – 12:30 PM
MT
(M1130-09-49) Controlled Release of Proteins with Hydralese
®
Formulations for Long-Acting Implants
Favorite
11:30 AM – 12:30 PM
MT
(M1130-09-51) Engineered Cocrystals to Improve Solution Behavior of Poorly Soluble NAR
Favorite
11:30 AM – 12:30 PM
MT
(M1130-09-52) Inclusion Complexes of Posaconazole with Hydroxypropyl- and Sulfobutylether-β-Cyclodextrins for Intravenous Injections: Formulation and Stability Studies
Favorite
11:30 AM – 12:30 PM
MT
(M1130-09-53) Thermoresponsive Polymeric Prodrug of Hydromorphone (ProGel-HMP) Provides Sustained Relief to Skeletal Pain in a Rodent Model of Femur Fracture
Favorite
11:30 AM – 12:30 PM
MT
(M1130-10-54) Advancing Treatment for Metastatic Triple Negative Breast Cancer: Liposomal Oncolytic Adenovirus as a Novel Neoadjuvant Therapy
Favorite
11:30 AM – 12:30 PM
MT
(M1130-10-56) Near-Infrared Assessment: A Potential Rapid Screening Tool for Pharmaceutical Quality Assessment
Favorite
11:30 AM – 12:30 PM
MT
(M1130-10-57) Evaluation of Lubricant Distribution in Tablets Using All-in-One Excipients
Favorite
11:30 AM – 12:30 PM
MT
(M1130-10-58) Mechanistic Investigation of Gamma Irradiation Effects on Physicochemical Stability of Excipients Used in Colloidal Injectable Suspensions
Favorite
11:30 AM – 12:30 PM
MT
(M1130-10-59) Prediction of Maximum Drug Loading in a Tablet Using Percolation Theory
Favorite
11:30 AM – 12:30 PM
MT
(M1130-11-60) Effect of Medium Viscosity on Swelling and Disintegration of Immediate Release Solid Oral Tablet
Favorite
11:30 AM – 12:30 PM
MT
(M1130-11-61) Development of Biorelevant Dissolution Methods for Potential Risk-Based Biowaivers of BCS Class IIa Compounds: Impact of pH, Buffer Capacity and Hydrodynamics of Dissolution Media
Favorite
11:30 AM – 12:30 PM
MT
(M1130-11-62) Network Analysis of Pharmaceutical Products from Hong Kong PIC/S GMP Manufacturers
Favorite
11:30 AM – 12:30 PM
MT
(M1130-11-63) Synthesis of Novel Surfactant for Formulating Cationic Nanoparticles
Favorite
11:30 AM – 12:30 PM
MT
(M1130-11-64) Decreased Crystal Plasticity by Solvation-The Case of Levofloxacin Acesulfame
Favorite
12:30 PM – 1:30 PM
MT
(M1230-01-01) Power of a Diverse Analytical Toolbox for Polysorbate 80 Degradation Risk Assessment and Control: Case Study for Liquid Formulation Development
Favorite
12:30 PM – 1:30 PM
MT
(M1230-01-02) Redox-Responsive Fattigated Nanoparticles Potentiate Lipid Accumulation and Controlled Doxorubicin Release for Boosting the Anti-Cancer Activity
Favorite
12:30 PM – 1:30 PM
MT
(M1230-01-03) Dual-Drug Ionic Liquid Complex Dextromethorphan Naproate with Enhancement of Physico-Chemical Properties than Parent Molecules
Favorite
12:30 PM – 1:30 PM
MT
(M1230-01-04) Week-Long Transdermal Delivery of an Anxiolytic Drug Using Tip-Loaded PVA Microneedles
Favorite
12:30 PM – 1:30 PM
MT
(M1230-01-05) Immobilization of Depolymerase Coating with Lay Down Bactericidal Activity on Biomedical Implants
Favorite
12:30 PM – 1:30 PM
MT
(M1230-01-06) Development of Inhalable CXCR4 Targeted Polymeric Nanoemulsions for Delivery of RNAi Therapeutics to Enhance Anti-PD-L1 Immunotherapy in Lung Tumors
Favorite
12:30 PM – 1:30 PM
MT
(M1230-02-07) Dispersome® as an Advanced Platform for Oral Bioenhancement
Favorite
12:30 PM – 1:30 PM
MT
(M1230-02-08) In Vitro – In Vivo Correlation Studies of Amorphous and Lipid-Based Oral Cannabidiol Formulations
Favorite
12:30 PM – 1:30 PM
MT
(M1230-02-09) Comparative Transcriptomic Profiling of Drug Metabolizing Enzymes and Drug Transporters in the Rabbit Ocular Sub-tissues
Favorite
12:30 PM – 1:30 PM
MT
(M1230-02-10) No Clinically Meaningful Pharmacokinetic Drug-Drug Interaction Between Berotralstat and the Progestin Oral Contraceptive Desogestrel
Favorite
12:30 PM – 1:30 PM
MT
(M1230-02-11) Novel Quantification Method for Evaluation of Hair Growth in Mice
Favorite
12:30 PM – 1:30 PM
MT
(M1230-02-12) Metabolite Identification of a Kratom Alkaloid Speciogynine in Human Liver Microsomes and Hepatocytes
Favorite
12:30 PM – 1:30 PM
MT
(M1230-03-14) Quality by Design Guided Development of Hydrogel-Forming Microneedle Array Patches for Enhanced Transdermal Delivery of Biomimetic Peptide Enfuvirtide
Favorite
12:30 PM – 1:30 PM
MT
(M1230-03-15) Coamorphous Nanoparticles Produced by Co-precipitation of Two Drugs Based on Liquid-Liquid Phase Separation: Improved Solubility and Membrane Permeability
Favorite
12:30 PM – 1:30 PM
MT
(M1230-03-16) Enhanced Skin and Follicular Delivery of Tazarotene from PLGA Nanoparticles for the Treatment of Acne and Psoriasis
Favorite
12:30 PM – 1:30 PM
MT
(M1230-03-17) Pioneering the Targeted Brain Delivery of Aspirin to Elicit COX-1&2 Inhibition, Protecting from Ischemic Stroke and Neurodegeneration
Favorite
12:30 PM – 1:30 PM
MT
(M1230-03-18) Multimodal Immunogene Therapy via Nanoparticle Delivery System
Favorite
12:30 PM – 1:30 PM
MT
(M1230-04-19) Guaifenesin: Discovery and Attributes of Novel Racemic Compound
Favorite
12:30 PM – 1:30 PM
MT
(M1230-04-21) Self-Assembling β-cyclodextrin siRNA Nanoparticle Complex in Silencing Mutant Huntingtin Protein (mHtt)
Favorite
12:30 PM – 1:30 PM
MT
(M1230-04-22) Novel Personalized Treatment for Multiple Myeloma: Multi-Antigen T Cell Hybridizers for T Cell Activation
Favorite
12:30 PM – 1:30 PM
MT
(M1230-04-23) Design, Synthesis, and Evaluation of Claudin-1 Inhibitors for the Treatment of Metastatic Colorectal Cancer
Favorite
12:30 PM – 1:30 PM
MT
(M1230-05-25) A Molecular Dynamics Study of the Impact of Water Content on Pre-nucleation Aggregates in Amorphous 2-Phenylamino Nicotinic Acid
Favorite
12:30 PM – 1:30 PM
MT
(M1230-05-26) Manufacturability, Stability, and In Vitro Release of 60% Drug Loaded Amorphous Nanoparticle Tablets of a BCS IV Compound: ABT-530
Favorite
12:30 PM – 1:30 PM
MT
(M1230-05-27) Dual Release of Lidocaine and Tizanidine from Coated and Monolithic Implants
Favorite
12:30 PM – 1:30 PM
MT
(M1230-05-28) Improved Dissolution and Pharmacokinetic Behaviors of Zerumbone upon Solid Lipid Nanoparticle Approach
Favorite
12:30 PM – 1:30 PM
MT
(M1230-05-29) Employing Hot Melt Extrusion and Vacuum Compression Molding to Develop Cannabidiol Solid Sedds for Improved Solubility
Favorite
12:30 PM – 1:30 PM
MT
(M1230-05-30) Exploration of the Utility of Bentonite for Developing a Pediatric Formulation of Everolimus
Favorite
12:30 PM – 1:30 PM
MT
(M1230-06-31) Manipulating the PLGA Terminal Group Chemistry Alters Electrostatic Controlled Release from Polymeric Microparticles
Favorite
12:30 PM – 1:30 PM
MT
(M1230-06-32) Identification of Small Molecule APJ Receptor Antagonists for Treatment of Cancers
Favorite
12:30 PM – 1:30 PM
MT
(M1230-06-33) Evaluation of Anti-Proliferative Effect of Vorinostat (a pan-HDAC Inhibitor) on Glioblastoma Multiforme Using 3-D Cell Culture Model of T98G
Favorite
12:30 PM – 1:30 PM
MT
(M1230-06-34) Influence of Quantitative Differences in Propylene Glycol on the Performance of Diclofenac Sodium Topical Gels
Favorite
12:30 PM – 1:30 PM
MT
(M1230-06-35) Pharmacokinetic Study of Delta-8-Tetrahydrocannabinol in Male Rats Using a Validated UPLC-MS/MS Method
Favorite
12:30 PM – 1:30 PM
MT
(M1230-06-36) A New Neurolysin Activator Ameliorates Brain Injury in Ischemic Stroke Mice
Favorite
12:30 PM – 1:30 PM
MT
(M1230-07-37) Local Controlled Delivery of an A3 Receptor Agonist Reduces Inflammation Associated with Contact Hypersensitivity
Favorite
12:30 PM – 1:30 PM
MT
(M1230-07-38) Improved Ibuprofen Tablet Formulation Using Co-Processed Excipients Containing Polyethylene Glycol 8000
Favorite
12:30 PM – 1:30 PM
MT
(M1230-07-39) A Comparative Approach in the Evaluation and Optimization of Enteric Coating for Tablet Formulation
Favorite
12:30 PM – 1:30 PM
MT
(M1230-07-40) Optimization of Excipients Attributes of Immediate Release Tablet Formulation Using Quality by Design
Favorite
12:30 PM – 1:30 PM
MT
(M1230-07-41) Investigation of the Dermal Delivery of Benzoyl Peroxide from Topically Applied Formulations In Vitro
Favorite
12:30 PM – 1:30 PM
MT
(M1230-09-48) Role of Low Nitrite (LN) Excipients in Mitigating N-Nitrosamine Drug Substance-Related Impurity (NDSRI) Formation in Drug Products
Favorite
12:30 PM – 1:30 PM
MT
(M1230-09-49) Microneedle-Based Co-Delivery System for Naproxen Sodium and Caffeine in Migraine Therapy
Favorite
12:30 PM – 1:30 PM
MT
(M1230-09-50) The Hidden Potential: Enhancing Doxycycline Dissolution and Aerodynamics with HPMC and Gelatin for Pulmonary Drug Delivery
Favorite
12:30 PM – 1:30 PM
MT
(M1230-09-51) Formulating Sustainable Solid Oral Tablets by Employing Digital Tools and Co-Processed Excipients
Favorite
12:30 PM – 1:30 PM
MT
(M1230-10-54) 3D-Printed Microneedles Delivering Regulatory Immune Cues to Antigen-Presenting Cells in the Skin Promote Immune Tolerance
Favorite
12:30 PM – 1:30 PM
MT
(M1230-10-56) Sodium Stearyl Fumarate vs. Magnesium Stearate: Understanding the Mechanism of Over-Lubrication
Favorite
12:30 PM – 1:30 PM
MT
(M1230-10-57) Formulation of an Oil-in-Hydrogel Anti-Adhesion System for Sustained Release of Liposomes-Encapsulated 5-Fluorouracil
Favorite
12:30 PM – 1:30 PM
MT
(M1230-10-58) Using AI-ML Modelling to Predict the Thawing Rates of Large Scale Frozen Protein Solutions
Favorite
12:30 PM – 1:30 PM
MT
(M1230-11-60) The Effect of Conventional Cooling Versus Controlled Ice Nucleation on Primary Drying Time
Favorite
12:30 PM – 1:30 PM
MT
(M1230-11-61) Development of Improved Chromatographic Methods for the Separation of Synthetic Peptide Medications and Associated Impurities
Favorite
12:30 PM – 1:30 PM
MT
(M1230-11-62) Physical Stability of Ritonavir Crystallized in Space
Favorite
12:30 PM – 1:30 PM
MT
(M1230-11-63) Prediction Model for the Dry Film Thickness in the Continuous Manufacturing of Oral Films
Favorite
12:30 PM – 1:30 PM
MT
(M1230-11-64) A New Insight into the Effect of the Process Conditions on the Permeability of Powders
Favorite
12:30 PM – 1:30 PM
MT
(M1230-11-65) Local Heat Generation at Kneading Zone in Continuous Twin-Screw Melt Granulation: Exploring the Interplay of Processing Parameters and Binder Level for a Novel Thermal Binder
Favorite
1:30 PM – 2:30 PM
MT
(M1330-01-01) The Anti-Colon Cancer Potential of Succinylated Curcumin Encapsulated in Mannosylated Chitosan
Favorite
1:30 PM – 2:30 PM
MT
(M1330-01-02) Enhanced Permeability and Stability of Self-Assembled Fatty Acid-Conjugated Peptide Drug Nanoparticles for Oral Delivery
Favorite
1:30 PM – 2:30 PM
MT
(M1330-01-03) Developing Lipid Nanoparticles (LNPs) for mRNA Delivery in Pancreatic Cancer (PC)
Favorite
1:30 PM – 2:30 PM
MT
(M1330-01-04) The Non-GLP Dose Range-Finding Study on Lymphatic-Targeting of Cyclosporine in Mrl-lpr Mouse Model of SLE
Favorite
1:30 PM – 2:30 PM
MT
(M1330-01-05) Is a Minimally Invasive Amphotericin B Treatment Feasible? Nanocrystals-Loaded Microneedles for Cutaneous Leishmaniasis
Favorite
1:30 PM – 2:30 PM
MT
(M1330-01-06) Formulation of a Poorly Soluble Antiviral Drug as Microparticle Powder for Nasal Breath Intake Against Respiratory Infections
Favorite
1:30 PM – 2:30 PM
MT
(M1330-02-07) Understanding the Influence of Drug Metabolizing Enzyme Activity on Small Molecule Stability Within a Commonly Used Preclinical Tumor Model
Favorite
1:30 PM – 2:30 PM
MT
(M1330-02-08) In Vitro Assays for the Evaluation of Innate Immunogenicity in Generic Peptide Drug Products
Favorite
1:30 PM – 2:30 PM
MT
(M1330-02-09) Translational Pharmacokinetic Assessment of
Mitragyna Speciosa
(kratom), a Potential Treatment Option for Opioid Use Disorder
Favorite
1:30 PM – 2:30 PM
MT
(M1330-02-10) Development of a Mitra Tip Extraction Assay Coupled with LC-MS/MS for Quantitation of L-Citrulline, L-Arginine, and L-Argininosuccinic Acid: A Novel Approach for Biomarker Analysis
Favorite
1:30 PM – 2:30 PM
MT
(M1330-02-11) Toxicokinetics of cP12, a Fibronectin-Derived Peptides, in Rats and Dogs Following a Single Intravenous Injection in an Expanded Acute Toxicity Study
Favorite
1:30 PM – 2:30 PM
MT
(M1330-02-12) Multi-Strain Sars-Cov-2 Neutralization Assay Qualification
Favorite
1:30 PM – 2:30 PM
MT
(M1330-03-13) Artificial Extracorporeal Replicate for Drugs (AER
x
): A Low-Cost Extracorporeal Membrane Oxygenator (ECMO) Mimic for High Throughput Drug Screening
Favorite
1:30 PM – 2:30 PM
MT
(M1330-03-14) Mesenchymal Stem Cell-Based Drug Delivery Approach for Effective Management of Pancreatic Cancer
Favorite
1:30 PM – 2:30 PM
MT
(M1330-03-15) Thermal Stability and Controlled Release of Fattigated Vaccine Antigen in Human Serum Albumin Nanoparticle
Favorite
1:30 PM – 2:30 PM
MT
(M1330-03-16) From Desired Dissolution Profile To Particle Size Distribution: Solving The Inverse Problem
Favorite
1:30 PM – 2:30 PM
MT
(M1330-03-17) Development, Characterization, and In Vitro Digestion of C-phycocyanin-Whey Protein Isolate-Zein Nanoparticles for Pharmaceutical Applications
Favorite
1:30 PM – 2:30 PM
MT
(M1330-03-18) Can Individual Taste Perceptions Bias the Results of Taste Panel Studies? Lessons Learned from an In Vivo Investigation with Paediatric ODMTs
Favorite
1:30 PM – 2:30 PM
MT
(M1330-04-19) Stromal Fibrin Inhibition Shapes Immune Infiltration Landscape of Pancreatic Ductal Adenocarcinoma
Favorite
1:30 PM – 2:30 PM
MT
(M1330-04-20) Immunomodulation Improves Cancer Cell Clearance During Multi-Antigen T Cell Hybridizer Therapy
Favorite
1:30 PM – 2:30 PM
MT
(M1330-04-22) In Silico Evaluation of Coumarin Derivatives as Potential Antioxidant Agents on Psoriasis Treatment
Favorite
1:30 PM – 2:30 PM
MT
(M1330-04-24) High-Performance Liquid Chromatography Method with Refractive-Index Detection for Quantitation of Memantine Hydrochloride in Memantine Hydrochloride Extended-Release Dissolution Samples
Favorite
1:30 PM – 2:30 PM
MT
(M1330-05-25) Generalization of the Tabletability Equation for Describing Powder Properties as a Function of Compaction Pressure
Favorite
1:30 PM – 2:30 PM
MT
(M1330-05-27) Design of Foamable Microemulsions for Vaginal Antifungal Drug Delivery
Favorite
1:30 PM – 2:30 PM
MT
(M1330-05-28) Application of Acid-Base Supersolubilization Principle to Telmisartan, a Weakly Acidic, High Melting, and Low Solubility Drug, to Lower Hot Melt Extrusion Temperature and Increase Drug Dissolution
Favorite
1:30 PM – 2:30 PM
MT
(M1330-05-29) Self-Nanoemulsifying Systems Containing Ionic Liquids of Rilpivirine for Improved Oral Bioavailability and Penetration in the HIV Sanctuary Sites
Favorite
1:30 PM – 2:30 PM
MT
(M1330-05-30) Investigating Partial Trehalose Crystallization During Lyophilization of Proteins
Favorite
1:30 PM – 2:30 PM
MT
(M1330-06-31) Optimising the Extraction of Oligonucleotides by SPE
Favorite
1:30 PM – 2:30 PM
MT
(M1330-06-32) Quantifying and Mapping ATP Distribution Within Tissues to Inform Targeted Therapeutic Strategies in Drug Development
Favorite
1:30 PM – 2:30 PM
MT
(M1330-06-33) Plasma and Liver Pharmacolipidodynamics of Gefitinib after Intravenous Administration to Mice Using LC-MS/MS and MS Imaging
Favorite
1:30 PM – 2:30 PM
MT
(M1330-06-34) Use of Derivatization for a Sensitive and Selective Liquid Chromatography–Mass Spectrometry Method for Quantification of Acetaldehyde in Plasma
Favorite
1:30 PM – 2:30 PM
MT
(M1330-06-35) In Vitro Irritability, Toxicity, and Anti-Inflammatory Activity of Rosehip Oil Emulsion
Favorite
1:30 PM – 2:30 PM
MT
(M1330-06-36) Establishment of an Immunoassay to Quantify Total TL1α Target in Monkey Serum Samples
Favorite
1:30 PM – 2:30 PM
MT
(M1330-07-37) Immunoactive Nanoparticle Boosted cDC1 for In Situ Cancer Immunotherapy
Favorite
1:30 PM – 2:30 PM
MT
(M1330-07-38) Proof of Concept In Situ Salt Formation during Amorphous Solid Dispersion Fabrication to Improve Physical Stability and Drug Release Performance
Favorite
1:30 PM – 2:30 PM
MT
(M1330-07-39) Optimized Prime: A Transformative LNP Composition for Scalable RNA Vaccines
Favorite
1:30 PM – 2:30 PM
MT
(M1330-07-40) Development of Caffeine Customized-Release Tablets Using 3D Printing System and IVIVC Prediction
Favorite
1:30 PM – 2:30 PM
MT
(M1330-07-41) Manufacturing and Formulation Impacts on Colloidal Speciation in ASD Dosage Forms
Favorite
1:30 PM – 2:30 PM
MT
(M1330-09-49) Eliminating Operator Dependence from Gelling Agent Addition - Improving the Robustness and Processing Time of Semi-Solid Dosage Forms Without Impacting the Viscosity or Aesthetics
Favorite
1:30 PM – 2:30 PM
MT
(M1330-09-50) Bioequivalence Prediction with Dissolution-Permeation Set Up and tinyTim for Amorphous Solid Dispersion Manufactured by a Novel Co-precipitation Process and Spray Drying
Favorite
1:30 PM – 2:30 PM
MT
(M1330-09-51) Synthesis and Characterization of Nanostructured Lipid Carriers (NLC) with Bile Salts: Sodium Deoxycholate (SDC), Sodium Deoxyglycholate (SDGC) and Sodium Deoxytaurocholate (SDTC)
Favorite
1:30 PM – 2:30 PM
MT
(M1330-09-52) Non-Destructive Quality Control of Medicines Produced through 3D Printing in a Hospital Using Two Handheld Spectrometers
Favorite
1:30 PM – 2:30 PM
MT
(M1330-10-54) DSC vs. DVS: Determining the Moisture-Induced Tg vs. RH of Hygroscopic Materials
Favorite
1:30 PM – 2:30 PM
MT
(M1330-10-55) Evaluation of Critical Microstructural and Performance Attributes of Azelaic Acid Topical Gels
Favorite
1:30 PM – 2:30 PM
MT
(M1330-10-56) Comparative Study of Suitability for Wet Continuous Manufacturing Process Using MCC with Different Characteristics - Part 2
Favorite
1:30 PM – 2:30 PM
MT
(M1330-10-57) Enhancing Tablet Manufacturing Flexibility: Design Space Determination with Compaction Simulator
Favorite
1:30 PM – 2:30 PM
MT
(M1330-10-58) A Multiple Component, Indirect Analysis of Ammonium: Analysis of Sulfate Ion in a Commercial Biotherapeutic via HPLC to Measure Ammonium Content
Favorite
1:30 PM – 2:30 PM
MT
(M1330-10-59) Dissolution Method Development for Amorphous Solid Dispersions-Based Oral Drug Products
Favorite
1:30 PM – 2:30 PM
MT
(M1330-11-60) The Effects of Interfering Viral Particles on the Probability of Detecting Replication-Competent Adeno-Associated Virus (rcAAV) in a Replication-Based Cell Assay
Favorite
1:30 PM – 2:30 PM
MT
(M1330-11-61) Performance Verification Variations Within Mechanical Calibration Allowance of Paddle Apparatus with Standard and Apex Vessels
Favorite
1:30 PM – 2:30 PM
MT
(M1330-11-62) Simultaneous Detection of Camostat/Niclosamide Cocrystal and Its Related Impurities via Analytical Quality by Design
Favorite
1:30 PM – 2:30 PM
MT
(M1330-11-65) Compression Process Optimzation Using 2
3
Full Factorial Design of Experiments
Favorite
2:30 PM – 3:30 PM
MT
(M1430-01-01) Engineering Novel Antibody-Drug Conjugates with Dual Payloads to Improve the Incidence of Drug Resistance Associated with the Use of Antibody-Drug Conjugates in Oncology
Favorite
2:30 PM – 3:30 PM
MT
(M1430-01-02) Mixture of Immediate-Release Beads and Controlled-Release Beads to Form Sodium Oxybate Extended-Release Drug Product (LUMRYZ
TM
)
Favorite
2:30 PM – 3:30 PM
MT
(M1430-01-03) Development of a Coextrusion Process to Prepare Etonogestrel Long-Acting Implant
Favorite
2:30 PM – 3:30 PM
MT
(M1430-01-04) Formulation and In Vitro Evaluation of Carrageenan Based Gummies
Favorite
2:30 PM – 3:30 PM
MT
(M1430-01-05) Formulation and Skin Delivery of Quercetin Loaded PAMAM Dendrimer-Based Gel for Potential Anti-Inflammatory and Antioxidant Effect
Favorite
2:30 PM – 3:30 PM
MT
(M1430-01-06) Formulation Effects of Marketed Oral Cavity Products on In Vitro Buccal Permeability
Favorite
2:30 PM – 3:30 PM
MT
(M1430-02-07) An Overview of Cross-Referencing Approaches to Support Generic Drug Approval
Favorite
2:30 PM – 3:30 PM
MT
(M1430-02-08) Transcriptomic Analysis Reveals that
Nymphaea odorata
Extracts and Fractions Upregulate the Apoptosis, Autophagy, and Unfolded Protein Canonical Pathways in MCF-7 Cells
Favorite
2:30 PM – 3:30 PM
MT
(M1430-02-09) A PBPK Model for Prediction of Apixaban and Rivaroxaban Secretion into Milk
Favorite
2:30 PM – 3:30 PM
MT
(M1430-02-10) Population Pharmacokinetic Modeling of Time-Varying Effects of Anti-Drug Antibody Formation on the Pharmacokinetics of a Human Monoclonal Antibody in a Rodent Model
Favorite
2:30 PM – 3:30 PM
MT
(M1430-02-11) Common Bioequivalence (BE) Deficiencies Identified in ANDAs Associated with Solid Oral Extended-Release Drugs in Various Therapeutic Areas: A Retrospective Survey of BE Study Data Submitted to the FDA
Favorite
2:30 PM – 3:30 PM
MT
(M1430-02-12) Integrating Omics Data Through AI: Predicting Novel Therapeutic Targets for Therapy-Resistant Cancer Patients
Favorite
2:30 PM – 3:30 PM
MT
(M1430-03-13) Combination eEF2K Gene and Drug Delivery for Treatment of Breast Cancer
Favorite
2:30 PM – 3:30 PM
MT
(M1430-03-14) Intravitreal Delivery of Anti-Inflammatory Agents via Thermo-Responsive Gel-Forming Biodegradable Triblock Copolymers
Favorite
2:30 PM – 3:30 PM
MT
(M1430-03-15) Physicochemical Properties and Controlled Peptide Drug Release via Hydrophobicity Modulation of Albumin-Oleic Acid Conjugate
Favorite
2:30 PM – 3:30 PM
MT
(M1430-03-17) Targeted Antiretroviral Therapy Using Controlled Release Polymeric Nanoparticles for Brain Viral Load Reduction and Management of HIV Associated Neurocognitive Disorder (HAND)
Favorite
2:30 PM – 3:30 PM
MT
(M1430-03-18) Optimizing Semi-Solid Extrusion 3D Printed Hydrochlorothiazide Tablets: The Role of Rheological Properties and Drying Methods on Structure and Appearance
Favorite
2:30 PM – 3:30 PM
MT
(M1430-04-19) Discovery of BB99: A Potent T2R54 (TAS2R39) Antagonist that Blocks the Bitterness of Select Active Pharmaceutical Ingredients (APIs)
Favorite
2:30 PM – 3:30 PM
MT
(M1430-04-20) Coarse-Grained Molecular Dynamics Simulations Evaluating Formation and Structural Stability of Nystatin-Loaded DOPC and DPPC Vesicles
Favorite
2:30 PM – 3:30 PM
MT
(M1430-04-21) Anti-CD47 Peptide Combined with Oncolytic Vesiculovirus-Driven Intratumoral Immunotherapy for Colorectal Cancer
Favorite
2:30 PM – 3:30 PM
MT
(M1430-04-22) Discovery and Development of a New Therapeutic Product for the Treatment Long Covid
Favorite
2:30 PM – 3:30 PM
MT
(M1430-04-23) Combination Therapy of BRD4/PI3K Dual Inhibitor and a Novel Hedgehog Inhibitor for the Treatment of Sonic Hedgehog and MYC-Amplified Medulloblastoma
Favorite
2:30 PM – 3:30 PM
MT
(M1430-04-24) Gut Microbiota-Based Bioassay for the Quality Control of Dendrobium from Different Sources
Favorite
2:30 PM – 3:30 PM
MT
(M1430-05-25) Hydrolysis of Cellulose Acetate Phthalate and Hydroxypropyl Methylcellulose Phthalate in Amorphous Solid Dispersions
Favorite
2:30 PM – 3:30 PM
MT
(M1430-05-26) Rapid and Reliable Nitrite Content Analysis in Pharmaceutical Excipients with the ACQUITY
TM
QDa
TM
II Mass Detector
Favorite
2:30 PM – 3:30 PM
MT
(M1430-05-27) Self-Emulsifying NanoPODS (Nano-PND Oral Delivery Systems) for Oral Delivery of PND1186: In Silico Modeling for Bioavailability Estimation
Favorite
2:30 PM – 3:30 PM
MT
(M1430-05-28) Development of 3D Printed Tablets of Weakly Acidic Drug-Flurbiprofen by Acid-Base Super-Solubilization at Lower Extrusion Temperature and Improved Printability
Favorite
2:30 PM – 3:30 PM
MT
(M1430-05-29) Addressing the Opioid Crisis: Assessing Abuse-Deterrent Formulations Utilizing Ion-Exchange Resin Complexation Processed via Twin-Screw Granulation for Improved Safety and Effectiveness
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2:30 PM – 3:30 PM
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(M1430-05-30) Formulation Development of PEGylated Deferoxamine Carbon Nanoparticles Gel for Topical Application
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2:30 PM – 3:30 PM
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(M1430-06-31) A Sensitive Bioanalysis Method for Antisense Oligonucleotides using LC-MS/MS
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2:30 PM – 3:30 PM
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(M1430-06-32) Development of Sensitive Method for Antisense Oligonucleotide Therapeutics Using SIMOA Technology
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2:30 PM – 3:30 PM
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(M1430-06-33) The Impact of Unique Stable Label Peptide Internal Standards toward Large Molecule Applications for LC-MS/MS
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2:30 PM – 3:30 PM
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(M1430-06-34) Validated Biomarker Assay for the Analysis of Coproporphyrin I and Coproporphyrin III in Human Plasma
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2:30 PM – 3:30 PM
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(M1430-06-35) Avoiding Pitfalls in Selecting Quality Control Concentrations in Surrogate Matrix Approach for Endogenous Drugs
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2:30 PM – 3:30 PM
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(M1430-07-37) Intracellular Trafficking of Cationic Bicelles and siRNA Cargo in an In Vitro BBB Model
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2:30 PM – 3:30 PM
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(M1430-07-38) Nanotechnological Approach to Cannabidiol Delivery: Production and Characterization of Microemulsion for Oral Administration
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2:30 PM – 3:30 PM
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(M1430-07-39) Targeting Resistant Pathogens: The Promise of Vancomycin-Silver Nanoparticle Hybrids Against Vancomycin-Intermediate Staphylococcus Aureus (VISA)
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2:30 PM – 3:30 PM
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(M1430-07-40) Mechanistic PBPK Modelling of Itraconazole Oral Solutions: Evaluating HP-β-CD Impact on Solubility and Drug-Drug Interactions
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2:30 PM – 3:30 PM
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(M1430-07-41) Functional Coatings with Cellulose Acetate Grade Combinations in Osmotic Devices – Process Optimization and Release Modulation of Metoprolol Succinate
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2:30 PM – 3:30 PM
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(M1430-09-48) Combining Arrhenius Kinetics and Monte Carlo Simulation to Enhance Stability Prediction for Antibodies
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2:30 PM – 3:30 PM
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(M1430-09-49) Remote Encapsulation of Exenatide in PLGA Microspheres Using Cationic Excipients
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2:30 PM – 3:30 PM
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(M1430-09-50) Creating Personalized 3D-Printed Finger Splints with Ibuprofen-Loaded Nanofibers for Quicker Healing Using CT Scans
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2:30 PM – 3:30 PM
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(M1430-09-51) Aerosolizable Drug Loaded Superparamagnetic Iron Oxide Nanoparticle Theranostic for Pulmonary Tuberculosis
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2:30 PM – 3:30 PM
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(M1430-09-52) Development of Dry Powder Formulation of PAV-104 for Pulmonary Drug Delivery
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2:30 PM – 3:30 PM
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(M1430-10-54) Designing Spray Dried Particles with a Pressure Nozzle at Small Scale
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2:30 PM – 3:30 PM
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(M1430-10-55) Formulation Development of High Drug Loaded, Stable Amorphous Solid Dispersions (ASDs) Through Spray Drying: An Industrial Perspective Case Study
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2:30 PM – 3:30 PM
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(M1430-10-56) Material Sparing Dry Granulation via RoCo Simulation Enables Technical Transfer of SDI-Based Formulations
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2:30 PM – 3:30 PM
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(M1430-10-57) Development of a Single-Vial Drug Release Assay Utilizing Bio-Beads SM-2 Resin to Evaluate Doxorubicin Liposomes
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2:30 PM – 3:30 PM
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(M1430-10-58) Rapid Material-Sparing Approach to Address Hairline Fractures in Low Drug Load Tablets via Compaction Simulation
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2:30 PM – 3:30 PM
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(M1430-10-59) High Drug Load Metformin ER 1000 mg Tablets Processed via Roller Compaction in Combination with High Molecular Weight HPC
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2:30 PM – 3:30 PM
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(M1430-11-60) Characterization of Protein Antigens in Liposomal Vaccines Using Differential Scanning Fluorimetry
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2:30 PM – 3:30 PM
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(M1430-11-61) Toward Improving the In Vitro, In Vivo Correlation of Lipid-Based Formulations Using a Simplified Gastro-Intestinal Lipolysis Protocol
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2:30 PM – 3:30 PM
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(M1430-11-63) Going Greener with the USP 621 Globally Harmonized Pharmacopeial Guidance for Liquid Chromatography
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2:30 PM – 3:30 PM
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(M1430-11-64) System Robustness and Best Practices of a High Throughput LC-MS Method for Cell Culture Media Nutrient and Metabolite Analysis
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2:30 PM – 3:30 PM
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(M1430-11-65) Particle Engineering Approach to Formulating Hot Melt Extrusion Amorphous Solid Dispersion Tablets
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3:30 PM – 4:30 PM
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(M1530-01-01) Exploring AAV Capsid Aggregation: Molecular Simulations of Capsid Interactions in Varied Ionic and Surfactant Environments
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3:30 PM – 4:30 PM
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(M1530-01-02) 2-Stage Dissolution Method for Drug Release Testing of Sodium Oxybate Extended-Release Drug Product LUMRYZ
TM
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3:30 PM – 4:30 PM
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(M1530-01-03) Targeted Cell-Penetrating Peptide-Drug Conjugates for the Treatment of Pancreatic Cancer
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3:30 PM – 4:30 PM
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(M1530-01-04) Exploring Drug Formulation Expert Perspectives on High-Concentration Subcutaneous Formulation Development: A Survey Analysis of Infrastructure, Stakeholder Preferences, and Perceptions
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3:30 PM – 4:30 PM
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(M1530-01-05) Evaluation of a TiO2-Free PVA-Based Film Coating System with Improved Opacity and Color Uniformity
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3:30 PM – 4:30 PM
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(M1530-02-07) Evaluation of the Pharmacokinetics and Abuse Potential of Intranasally Administered Extended-Release Oxycodone and Naloxone Abuse-Deterrent Formulations Milled to Different Particle Sizes
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3:30 PM – 4:30 PM
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(M1530-02-08) PK/PD Modeling for Liver Targeting LNP Formulated tRNA in Transgenic Mice Containing a Premature Termination Codon on the Human Methylmalonyl-CoA Mutase (hMMut)
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3:30 PM – 4:30 PM
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(M1530-02-09) Dermal PBPK Model for Psoriatic Skin: Clobetasol Propionate Case Study
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3:30 PM – 4:30 PM
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(M1530-02-10) Predicting Belumosudil Drug-Drug Interactions Using a Physiologically Based Pharmacokinetic Model
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3:30 PM – 4:30 PM
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(M1530-02-11) Circumvention of Targeted Anticancer Drug Resistance by Standardized Yunzhi Extract
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3:30 PM – 4:30 PM
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(M1530-02-12) Characterizing Interactions of RO7297089, an Anti-B-Cell Maturation Antigen (BCMA)/CD16A Bispecific Tetravalent Antibody with Shed Soluble CD16A Antigen in Plasma In Vitro
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3:30 PM – 4:30 PM
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(M1530-03-13) ALD Nano Coating on Lyophilized and Spray Dried Biologics: Feasibility and Stability Improvement
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3:30 PM – 4:30 PM
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(M1530-03-15) Biopredictive Dissolution of Budesonide Enteric Pellets under Simulated Fasted Intake Conditions
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3:30 PM – 4:30 PM
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(M1530-03-16) Development and Optimization of Oral Dissolving Film Formulation Containing Psilocybin
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3:30 PM – 4:30 PM
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(M1530-03-17) Downstreaming Amorphous Solid Dispersions: Direct Compression of Free-Flowing Telmisartan Microparticles
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3:30 PM – 4:30 PM
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(M1530-04-19) Bioengineering Models to Study Cell-Specific Durotaxis in Pulmonary Arterial Hypertension
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3:30 PM – 4:30 PM
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(M1530-04-20) Polymer Effects on Kolliphor P407's Mucoadhesion
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3:30 PM – 4:30 PM
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(M1530-04-21) From Sequence to Binding Clones, a Novel Computational Platform for Nanobody Discovery
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3:30 PM – 4:30 PM
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(M1530-04-22) Anti-Viral and Anti-Inflammatory Effects of Novel PPARγ Agonist, INT131, in an EcoHIV Mouse Model: Relevance to the Treatment of HIV-Associated Neurocognitive Disorders
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3:30 PM – 4:30 PM
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(M1530-04-23) Deciphering Sub-Therapeutic Risks: Integrating In Vitro Release and Modeling for Lamotrigine Extended-Release Tablets
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3:30 PM – 4:30 PM
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(M1530-04-24) Isolation and Biological Activity Evaluations of Exosome-Like Nanovesicles Derived from
Dendrobium officinale
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3:30 PM – 4:30 PM
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(M1530-05-25) Enhanced Understanding of the Relationship between Drug Product Structure and Its Performance by Using Modeling and Simulation - A Case Study with Dapsone Topical Gel
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3:30 PM – 4:30 PM
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(M1530-06-31) Insulin Resistance Triggers Histamine Release from Endothelial Cells Which Disrupts Endothelial Barrier Function and Causes Vasoconstriction
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3:30 PM – 4:30 PM
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(M1530-06-32) How the Physical Form of Mannitol Affects Tablet Ejection Force
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3:30 PM – 4:30 PM
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(M1530-06-33) Development of 3D-Printed Expandable Gastroretentive Drug Delivery System by Applying the Design of Experiment Approach
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3:30 PM – 4:30 PM
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(M1530-06-34) Molecular Dynamics Study Using Coarse-Grained Simulation with Martini Force Field for Structural Stability and Formation of Docetaxel Loaded DOPC and DPPC Lipid Vesicle
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3:30 PM – 4:30 PM
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(M1530-06-35) Formulation and Evaluation of Antibacterial Activity of K21 Topical Liquid and Gel Formulations
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3:30 PM – 4:30 PM
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(M1530-06-36) Platform Approach for Identifying the Most Functional and Developable Bispecific T Cell Engager
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3:30 PM – 4:30 PM
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(M1530-07-37) Optimization of 3D Printed Tablets Using Artificial Intelligence and Machine Learning
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3:30 PM – 4:30 PM
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(M1530-07-38) Twin Screw Melt Granulation: Enhancing Solubility and Release Profile of Simvastatin Using Miscible and Immiscible Polymer Blends
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3:30 PM – 4:30 PM
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(M1530-07-39) Compression-Induced Destabilization in Chlorpropamide-PVPVA Amorphous Solid Dispersions
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3:30 PM – 4:30 PM
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(M1530-07-40) Mannitol vs Lactose in Twin Screw Continuous Wet Granulation Using New Binder
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3:30 PM – 4:30 PM
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(M1530-07-41) Preparation and Characterization of Hydrogel Microneedles Using Gantrez®S-97 and Hyaluronic Acid
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3:30 PM – 4:30 PM
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(M1530-09-48) Dual Adjuvanted Ionizable Lipid Nanoparticles for Vaccine Delivery
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3:30 PM – 4:30 PM
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(M1530-09-50) Exploring Manufacturing Techniques for Enhancing the Solubility of Fenbendazole: A Comparative Study of Hot-Melt Extrusion, Spray Drying, and KinetiSol® Processing
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3:30 PM – 4:30 PM
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(M1530-09-51) Influence of Lyophilization Process Conditions on Crystallization Behavior and Formulation Stability of Doxycycline for Injection
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3:30 PM – 4:30 PM
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(M1530-09-52) Mass Transport Modeling and In Silico Formulation of Osmotic Controlled Release Tablets with Microscopy-Based Digital Twins
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3:30 PM – 4:30 PM
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(M1530-10-54) Development of an Aerosolizable Dry Powder of Mycobacteriophage D29 Using Thin-Film Freeze-Drying
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3:30 PM – 4:30 PM
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(M1530-10-55) Using Dissolution-Permeation Systems and In Silico PBPK Modeling for Food Effect Prediction of a BCS Class II Drug
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3:30 PM – 4:30 PM
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(M1530-10-56) Enhancing the Solubilization and Permeation of Fenofibrate: A Comparative Study of Free Form, PEG and SEDDS Formulations
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3:30 PM – 4:30 PM
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(M1530-10-57) Innovative Moisture Activated Dry Granulation (MADG) with Mesoporous Silica vs Wet Granulation: A Comparative Study
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3:30 PM – 4:30 PM
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(M1530-10-58) In Vivo Bioavailability Enhancement of Abiraterone Acetate Dispersome
®
Formulations
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3:30 PM – 4:30 PM
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(M1530-10-59) Antimicrobial Polymer-siRNA Polyplexes as a Dual-Mode Platform for the Treatment of Wound Biofilm Infection and Inflammation Control
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3:30 PM – 4:30 PM
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(M1530-11-60) Impact of X-Ray Micro-CT Resolution on Quantification of Quality Attributes and Simulated Mass Transport Properties of Lyophilized Products
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3:30 PM – 4:30 PM
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(M1530-11-61) Evaluating Zeta Potential's Role in Monoclonal Antibody Manufacturing and Medical Application
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3:30 PM – 4:30 PM
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(M1530-11-62) Method Development and Validation for Leachable Silicone Oil in Pharmaceutical Drug Products by Graphite Furnace AAS
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3:30 PM – 4:30 PM
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(M1530-11-63) Safe and Effective Analysis of High Potency Compounds Using Solid-State NMR Spectroscopy
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3:30 PM – 4:30 PM
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(M1530-11-65) Investigation of Dissolution and Permeation Properties of Amorphous Drug Particles Dispersed in Wax-Based Formulations
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