Discovery and Basic Research

(T0930-04-19) Gemcitabine/Doxorubicin-Combination Polymer-Drug Conjugate Synthesized by SPAAC Click Chemistry: Characterization and Evaluation in OVCAR-3 Ovarian Cancer Cells

(M0930-04-19) Genetically Engineered PD-L1 Targeted Exosomes for Immunotherapy of Doxorubicin Resistant Triple Negative Breast Cancers

(W0930-04-19) Quantitative Phase Imaging for Evaluation of the Radioprotective Effects of Synthetic Glycosaminoglycans on Immune Cells

(M0930-04-20) An Innovative Dual Action Antibiotic Adjuvant Strategy Using Ionic Liquid toward Synergistic Restoration of Activity in MDRO and Enhancing Antimicrobial Activity Against MRSA

(T0930-04-20) Effect of Processing Method on Release Profile of Fenofibrate Amorphous Solid Dispersion Prepared by Hot Melt Extrusion and 3D Printing

(W0930-04-20) Kruppel-Like Factor 2 (KLF2) Reduces Parameters of Coronavirus Disease-Related Pathogenesis

(W0930-04-21) Combination Therapy with Carboplatin and miR-5193/149-5p Mimics Against PD-L1 and FOXM1 Axes Loaded in NK-EVs Show Synergistic Effects in Two EGFR-TKI-Resistant (PDX and H1975R) Lung Tumor Models

(M0930-04-21) Evaluation of the Blood-Brain Barrier Protective Effects of Metformin after Mixed Exposures to Cigarette Smoke, e-Cigarette Vapor, and Stroke Conditions

(T0930-04-21) Optimizing Immunotherapy of Ovarian Cancer — Nanomedicine Strategies for Heating ‘Cold’ Tumor with Concurrent PD-L1 Attenuation

(M0930-04-22) A Catalytic Aldicarb Bioscavenger as a Treatment for Aldicarb Poisoning

(T0930-04-22) Mechanistic In Vitro Oral Absorption Model to Predict Mucosal Permeability of Oral Cavity Drug Products

(T0930-04-23) Poly(Acrylic Acid)/Poly(Vinyl Alcohol) Microarray Patches for Continuous Transdermal Delivery of Levodopa and Carbidopa: In Vitro and In Vivo Studies

(W0930-04-23) Three Dimensional Industrial DNA Nanorobot as a Functional Drug Delivery System

(T0930-04-24) Identifying the Role of Prion-Like Protein Doppel as a Novel Mediator of Pulmonary Arterial Hypertension

(W0930-04-24) Kidney Metabolomics Demonstrated the Energy Supply Upregulation by Radix Aconiti Lateralis Preparations in Rats

(M0930-04-24) Role of FLVCR2 in the Intestinal Choline Uptake in the Rat Model

(W1030-04-19) Beyond Voltage-Gated Sodium Channel (Na_v1.7): Exploring the Dual Role of GX201 and Sulfamethoxazole in Itch Management

(T1030-04-19) Cannabidiol and BDNF-Encapsulated Brain-Targeted Lipid Nanoparticles Reduce Inflammation, Lower Pathological Amyloid and Tau Levels, and Improve Cognition in Transgenic Models of Alzheimer’s disease

(M1030-04-19) Integrated Screening Platform of PDE for Lung Fibrosis Drug Discovery

(M1030-04-20) A Physiologically Based Pharmacokinetic Model of ¹⁸F-FMAU to Accompany Positron Emission Tomography in Humans

(W1030-04-20) Combination of Multivalent DR5 Receptor Clustering Agonists and Histone Deacetylase Inhibitors for Treatment of Colon Cancer

(T1030-04-20) Impact of Freeze-Thaw Cycles on Kolliphor P407's Thermogelling and Mucoadhesion

(T1030-04-21) A PARPi Screening Cascade to Facilitate Novel Drug Discovery

(W1030-04-21) Computational Pharmaceutics Approaches to Guide Lipid Based Formulation Development: How Data Mining Can Improve the Process

(M1030-04-21) Overexpression of Human ApoC3 in Mice Leads to Hypertriglyceridemia and Induces Key CVD-related Lipid Biomarkers

(M1030-04-22) Amyloid Beta Peptides Inhibit Insulin Trafficking at the Blood-Brain-Barrier in Alzheimer's disease Brain

(W1030-04-22) Antimicrobial Effects of S-nitrosothiols on Mycobacterium abscessus Biofilms

(T1030-04-22) Structure-Mechanical Property Relationship in Molecular Crystals for Predicting Tabletability

(T1030-04-23) Clinical Potential of UK4b as a New Generation of Anti-Inflammatory Drug to Treat Pain and Arthritis

(M1030-04-23) Formulation of a Triple-Action Nanoemulgel for Mild to Moderate Atopic Dermatitis: Impact on Skin's Mechanical and Antibacterial Properties

(M1030-04-24) Old Dog Learning a New Trick: Statins as Novel Inhibitors of Vascular PDE1A for Regulating Vasodilation and Blood Pressure

(T1030-04-24) Oren-gedoku-to, a Traditional Chinese Medicine, Prevents the Hyperglycemia Caused by Chronic Olanzapine Administration via Hypothalamic AMP-Activated Protein Kinase Activity

(M1130-04-19) Evaluation of Piperine Nanoparticles for FXTAS Treatment via CGG Repeat Drosophila Model

(W1130-04-19) GSH-Dependent Inhibition of Multidrug Resistance-Associated Protein 1 (MRP1) by ZW-1226

(T1130-04-19) Thioredoxin Interacting Protein (TXNIP) Inhibitor Protects Against Nicotine-Induced Podocyte Injury and Glomerular Sclerosis

(W1130-04-20) A Nano-Emulsion-Based Formulation of Sorafenib for Oral Bioavailability Enhancement and Repurposing against Non-small Cell Lung Cancer (NSCLC)

(T1130-04-20) Development of CD40 and HER2 Bispecific Antibodies for Enhanced Efficacy against HER2-Positive Tumors

(M1130-04-20) Impact of Macrophages on the Dissolution of Long-Acting Injectable Suspensions

(W1130-04-21) Identification of Potential Drug Combinations against BRAF V600E, p53 R273H HT-29 Colon Cancer Cells With and Without BRCA1 Knocked Down

(T1130-04-21) Plasmid ApoE2 Gene Delivery Across the Blood Brain Barrier for the Treatment of Alzheimer's Disease

(M1130-04-21) Rheological Adaptation of Hydrogels as Novel Preclinical In Vitro Model Substitutes for Human Vitreous Body

(W1130-04-22) Conformational Analysis of Alkyl/Aryl-α-O-Glycosides Using Isothermal Calorimetry: Stereo-Electronic Effects vs Hydrophobic Effect

(M1130-04-22) DEC2 Enhancement of Gemcitabine and Oxaliplatin Sensitivity of Pancreatic Cancer Cells through Suppression of IGFBP4

(T1130-04-22) Membrane Raft Redox Signalling Pathway Mediates Gut Microbial Metabolite TMAO-Induced NLRP3 Inflammasome Activation and Endothelial Dysfunction

(W1130-04-23) Implementation of a Semi-Automated Bead Extraction Procedure during Analyte Purification for High Throughput Immunogenicity Assays

(T1130-04-23) Regulation of VCAM-1 Expression by the Gut Microbial Metabolite Butyrate: Insights into Molecular Mechanisms

(T1130-04-24) Automated Workflow for Targeted Protein Degrader (TPD) Metabolite Identification Using Collision-Induced Dissociation (CID) and Electron-Activated Dissociation (EAD)

(M1130-04-24) Excitatory Amino Acid Transporter 2 (EAAT2): A Novel Therapeutic Target for Treatment of Alzheimer’s Disease (AD)

(T1130-06-31) ML-Driven Multi-Omics Analysis of Platelet-Rich Plasma: Differentiating Age-Related Biomarkers in Young and Old Individuals

(T1130-06-32) Humanized scFv Antibody Specific to an Extracellular Epitope of CCK-BR and Non-Opioid Therapies for Pain Management

(T1130-06-33) Investigating the Modelability of Human Oral Fraction Absorbed using Regulatory Data

(T1130-06-34) In Vitro Topical and Transdermal Delivery of 4-Phenylbutyric Acid Emulsome Loaded Foam Formulation for the Treatment of Chemical Warfare Agent-Induced Skin Injury

(T1130-06-35) Leveraging Machine Learning to Predict Clinical Adverse Events Driven by Target-Specific and Off-Target Binding

(T1130-06-36) Synthesis and Biological Evaluation of Dual Acting Sigma Receptor Ligands and Dopamine Transporter Ligands as Potential Treatment Cocaine Misuse

(W1230-04-19) Explainable Artificial Intelligence (XAI) for Generation of Library of Novel Potential Acetylcholinesterase Inhibitors

(M1230-04-19) Guaifenesin: Discovery and Attributes of Novel Racemic Compound

(T1230-04-19) Novel Targeted Drug and Metabolites Mapping Using DESI MRM Triple Quadrupole Mass Spectrometer Providing Increased Sensitivity and Acquisition Speed for Mass Spectrometry Imaging

(T1230-04-20) Mechanism of Curcumin Encapsulation by GCPQ Polymers: Unexpected Polymer Mesh (Matrix) Configuration Revealed by Atomistic Molecular Dynamics Simulations

(W1230-04-21) Assessment of Various Lactobacillus Spp as Potential Candidate for Treatment of Bacterial Vaginosis

(M1230-04-21) Self-Assembling β-cyclodextrin siRNA Nanoparticle Complex in Silencing Mutant Huntingtin Protein (mHtt)

(T1230-04-21) Synthesis and Characterization of Multi-Functionalized Chitosan Polymeric Micelles for Intranasal Delivery of pApoE2 to PS19 Tauopathy Mice

(W1230-04-22) Assessment of High Throughput Salt Screening Methodologies with Zwitterionic Compounds

(T1230-04-22) Investigation of the Anticonvulsant Effect of a New Oxazolidinone Derivative PH166 in Rats

(M1230-04-22) Novel Personalized Treatment for Multiple Myeloma: Multi-Antigen T Cell Hybridizers for T Cell Activation

(M1230-04-23) Design, Synthesis, and Evaluation of Claudin-1 Inhibitors for the Treatment of Metastatic Colorectal Cancer

(T1230-04-23) PBPK Modeling to Predict the Effect of Gastric pH on Bioequivalence of Dabigatran Etexilate Capsules

(W1230-04-24) Disruptions in Glucose and Amyloid-Beta Transport in Mouse Models Manifesting Metabolic Syndrome

(T1230-04-24) SPE-LC/MS Bioanalytical Quantification of the Biotherapeutic Peptide, Semaglutide from Plasma

(M1230-06-31) Manipulating the PLGA Terminal Group Chemistry Alters Electrostatic Controlled Release from Polymeric Microparticles

(M1230-06-32) Identification of Small Molecule APJ Receptor Antagonists for Treatment of Cancers

(M1230-06-33) Evaluation of Anti-Proliferative Effect of Vorinostat (a pan-HDAC Inhibitor) on Glioblastoma Multiforme Using 3-D Cell Culture Model of T98G

(M1230-06-34) Influence of Quantitative Differences in Propylene Glycol on the Performance of Diclofenac Sodium Topical Gels

(M1230-06-35) Pharmacokinetic Study of Delta-8-Tetrahydrocannabinol in Male Rats Using a Validated UPLC-MS/MS Method

(M1230-06-36) A New Neurolysin Activator Ameliorates Brain Injury in Ischemic Stroke Mice

(T1330-04-19) Non-Gelatin Film Coatings for Formulating Easy-to-Swallow Tablets

(M1330-04-19) Stromal Fibrin Inhibition Shapes Immune Infiltration Landscape of Pancreatic Ductal Adenocarcinoma

(M1330-04-20) Immunomodulation Improves Cancer Cell Clearance During Multi-Antigen T Cell Hybridizer Therapy

(T1330-04-20) Unveiling the Potential of Euterpe oleraceae Mart Seed Extract: Harnessing a Valuable By-Product for Pharmaceutical and Cosmetic Innovations

(T1330-04-21) Repurposing Paclitaxel via Vector-Guided Brain Delivery for Alzheimer Disease Treatment

(T1330-04-22) Exploring the Synergistic Potential of Fatty Acid Synthase Inhibitors and Geranylgeranyl Diphosphate Synthase Inhibitors in Myeloma Therapy

(M1330-04-22) In Silico Evaluation of Coumarin Derivatives as Potential Antioxidant Agents on Psoriasis Treatment

(T1330-04-23) Concurrent Effect of Lipids and Surfactants on Intestinal Drug Absorption: A Modeling Approach

(M1330-04-24) High-Performance Liquid Chromatography Method with Refractive-Index Detection for Quantitation of Memantine Hydrochloride in Memantine Hydrochloride Extended-Release Dissolution Samples

(M1430-04-19) Discovery of BB99: A Potent T2R54 (TAS2R39) Antagonist that Blocks the Bitterness of Select Active Pharmaceutical Ingredients (APIs)

(M1430-04-20) Coarse-Grained Molecular Dynamics Simulations Evaluating Formation and Structural Stability of Nystatin-Loaded DOPC and DPPC Vesicles

(T1430-04-20) In Situ Engineering of Tumor-Infiltrating Myeloid Cells Through Dendrimer-Based Lipid Nanoparticles

(M1430-04-21) Anti-CD47 Peptide Combined with Oncolytic Vesiculovirus-Driven Intratumoral Immunotherapy for Colorectal Cancer

(T1430-04-21) Mechanistic Model of In Vitro Intraoral Absorption of Buprenorphine for the Buccal and Gingival Mucosa

(M1430-04-22) Discovery and Development of a New Therapeutic Product for the Treatment Long Covid

(T1430-04-22) Novel PBPK-IVIVC Model to Predict Human Pharmacokinetics of Ruxolitinib Sustained-Release Formulations

(T1430-04-23) Boosting Checkpoint Immunotherapy with 2nd Generation HPMA Polymer Conjugates with Synchronous PD-L1 Attenuation

(M1430-04-23) Combination Therapy of BRD4/PI3K Dual Inhibitor and a Novel Hedgehog Inhibitor for the Treatment of Sonic Hedgehog and MYC-Amplified Medulloblastoma

(M1430-04-24) Gut Microbiota-Based Bioassay for the Quality Control of Dendrobium from Different Sources

(T1430-04-24) Method Optimization to Reduce Leakage of Encapsulated Protein from Ethylcellulose Microcapsules Using Bovine Serum Albumin as a Model Protein

(M1530-04-19) Bioengineering Models to Study Cell-Specific Durotaxis in Pulmonary Arterial Hypertension

(T1530-04-19) Lymphatic Targeting of Cyclosporine Improves Survival and Ameliorates Lupus-Like Autoimmune Disease in NZB/W Mice

(T1530-04-20) Anti-inflammatory and Analgesic Effects of Lapatinib in Rats

(M1530-04-20) Polymer Effects on Kolliphor P407's Mucoadhesion

(T1530-04-21) Development of a New Modality with Strong Cancer Immunotherapeutic Effect (CITE) for Multiple Myeloma Treatment

(M1530-04-21) From Sequence to Binding Clones, a Novel Computational Platform for Nanobody Discovery

(T1530-04-22) A Novel Hybrid Gasotransmitter for an Unmet Need of Glaucoma Therapy: A Proof-of-Concept Study

(M1530-04-22) Anti-Viral and Anti-Inflammatory Effects of Novel PPARγ Agonist, INT131, in an EcoHIV Mouse Model: Relevance to the Treatment of HIV-Associated Neurocognitive Disorders

(T1530-04-23) Constitution of a Helical Peptide on Exosome-Mimetic Vesicles

(M1530-04-23) Deciphering Sub-Therapeutic Risks: Integrating In Vitro Release and Modeling for Lamotrigine Extended-Release Tablets

(M1530-04-24) Isolation and Biological Activity Evaluations of Exosome-Like Nanovesicles Derived from Dendrobium officinale

(T1530-06-31) Discovery of Potassium Channel K_v7.4(KCNQ4) Selective Activator for the Treatment of Hearing loss

(M1530-06-31) Insulin Resistance Triggers Histamine Release from Endothelial Cells Which Disrupts Endothelial Barrier Function and Causes Vasoconstriction

(M1530-06-32) How the Physical Form of Mannitol Affects Tablet Ejection Force

(M1530-06-33) Development of 3D-Printed Expandable Gastroretentive Drug Delivery System by Applying the Design of Experiment Approach

(T1530-06-33) PAR-1 Selective Antagonist, SCH-79797 Dihydrochloride, Inhibits the Proliferation and Migration of the Metastatic Human Prostate Cancer (PC-3) Cells

(T1530-06-34) Ion-pairing Agent-Free SFC Separation of Polypeptides Using Automated Method Development Tools

(M1530-06-34) Molecular Dynamics Study Using Coarse-Grained Simulation with Martini Force Field for Structural Stability and Formation of Docetaxel Loaded DOPC and DPPC Lipid Vesicle

(T1530-06-35) Effect of Vasculotropic Dutch Amyloid Beta 40 on Blood-Brain Barrier (BBB) Endothelial Trafficking and Signaling

(M1530-06-35) Formulation and Evaluation of Antibacterial Activity of K21 Topical Liquid and Gel Formulations

(T1530-06-36) DoE-Based Optimization of RNA Nanosac Lyophilization for Cold-Chain-Free Storage and Transportation

(M1530-06-36) Platform Approach for Identifying the Most Functional and Developable Bispecific T Cell Engager